POST TRAUMATIC STRESS DISORDER

This study looks at whether adding medical cannabis to standard talk therapy can help veterans with PTSD feel less anxious, depressed, or suicidal. About 280 veterans who rarely use cannabis will be given cannabis or a placebo alongside therapy sessions. The goal is to see if can…

This study will test if cannabis-based treatments can help veterans with PTSD and suicidal thoughts. About 500 veterans who have used cannabis in the past year will be randomly assigned to receive either a cannabinoid treatment or a placebo. The goal is to see if the treatment re…

This study tests whether a single 25 mg dose of psilocybin (the active ingredient in magic mushrooms) combined with therapy can safely reduce PTSD symptoms in 35 cisgender women who were sexually assaulted at least 6 months ago. Participants will receive the drug in a controlled …

This study tests whether a single dose of psilocybin (the active ingredient in magic mushrooms) combined with mindfulness-based therapy can help people with posttraumatic stress disorder (PTSD). About 30 adults with PTSD will receive psilocybin along with either standard support …

This early study tests whether a single dose of psilocybin (the active ingredient in magic mushrooms) combined with intensive talk therapy can help people with chronic PTSD. Fifteen adults with moderate to severe symptoms will participate, and they must stop other psychiatric med…

This study tests whether the drug vilazodone can reduce PTSD symptoms in 200 active-duty service members and veterans. Participants receive either the drug or a placebo, and researchers track changes in symptom severity and safety over 12 weeks. The goal is to find a better treat…

This study looks at whether warm-water therapy followed by group exercise can help veterans with PTSD feel better. Fifty Danish veterans will take part in 16 weeks of one-on-one pool sessions, then 16 weeks of group exercises. The goal is to reduce PTSD symptoms, improve sleep, a…

This small pilot study tests whether a behavioral therapy delivered via telehealth can reduce PTSD and depression symptoms in people at high risk after a motor vehicle collision. Twenty adults who visit the emergency room within 72 hours of a crash and meet risk criteria will be …

This study tests a mobile app called Along With Me to help parents who have lost a pregnancy or baby in the first month. The app teaches ways to manage grief and stress. Some participants also get a peer guide for extra support. The goal is to see if the app reduces PTSD symptoms…

This study is developing and testing a new therapy (ACT-SHARE) for veterans who have PTSD, drink too much alcohol, and are having problems in their romantic relationships—including conflict or aggression. About 29 veterans will try the therapy to see if it helps them manage diffi…