New therapy targets Brain's 'Orienting' reflex to treat PTSD
NCT ID NCT04317820
First seen Nov 20, 2025 · Last updated Jun 22, 2026 · Updated 24 times
Summary
This study tests a therapy called Deep Brain Reorienting (DBR) for people with PTSD. DBR helps patients focus on physical tension linked to traumatic memories. 234 adults will be randomly assigned to either DBR or a waitlist, and researchers will measure changes in PTSD symptoms.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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London Health Sciences Centre - University Hospital
London, Ontario, N6A 5A5, Canada
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Deep Brain Reorienting (DBR) therapy
What this could lead to
If it works, this could offer a new, non-drug therapy to ease PTSD symptoms for many people.
What could go wrong
This is a relatively early study with a waitlist control, so results may be influenced by placebo or natural recovery. The therapy is also not widely available yet.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.