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Gut feeling: personalized bacteria may ease PTSD symptoms

NCT ID NCT07623967

Disease control Sponsor: Uzhhorod National University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether giving people with PTSD a personalized mix of gut bacteria (called pharmabiotics) can help their mental health. The researchers will track changes in PTSD symptoms, anxiety, depression, and thinking skills over 14 days. The goal is to see if fixing the gut microbiome can speed up recovery from PTSD.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

140 people

The number who actually took part.

Started

Jul 2024

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 60 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 18 to 60 years * Male or female sex * Presence of cognitive impairment, anxiety/depressive disorders, or post-traumatic stress disorder (PTSD) on the background of one or more of the following neurological conditions: * Mild to moderate traumatic brain injury (TBI) * Neuropathic pain * Vertebrobasilar syndrome * Chronic cerebral ischemia * Back pain * Blast injuries * Arterial hypertension * Degenerative-dystrophic spinal diseases * Spinal cord injury Exclusion Criteria: Pregnancy or history of pregnancy within the last 12 months * Multiple organ failure * Apallic state * Incurable patients * Prolonged coma * Severe traumatic brain injury * Psychiatric disorders (as a separate diagnosis) * Alcohol abuse * Current antibiotic therapy

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Conditions

The condition(s) this trial relates to.

brain ischemia combat disorder hypertensive disorder mixed anxiety and depressive disorder neuralgia post-traumatic stress disorder Psychological Well-Being spinal cord injury traumatic brain injury vertebral column disorder vertebrobasilar insufficiency

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PTSD - post traumatic stress disorder

Contacts and locations

Locations

  • Uzhhorod National University

    Uzhhorod, 88000, Ukraine

More trials for these conditions

Other studies related to the condition(s) this trial covers.