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Shock therapy for PTSD? brain stimulation shows promise in new trial

NCT ID NCT02900053

Symptom relief Sponsor: University Hospital, Tours Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a mild electrical brain stimulation technique called tDCS could improve the results of trauma-focused therapy for people with PTSD. 63 adults with chronic PTSD received either real tDCS or a fake version during therapy sessions. The goal was to see if the brain stimulation helped reduce PTSD symptoms more than therapy alone.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
transcranial direct current stimulation (tDCS)
What this could lead to
If it works, this could offer a new way to boost the effects of talk therapy for PTSD, helping people feel better faster.
What could go wrong
This is a small, early-stage study with only 63 people. The results may not apply to everyone, and the benefit over standard therapy is uncertain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

63 people

The number who actually took part.

Started

Jan 2017

Finished

Oct 2021

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Having a chronic PTSD (for more than 3 months and less than 10 years) without modification of SSRI long-term treatment for more than 4 weeks * Between 18 and 65 years-old * Effective contraception for women, or inability of procreate because of medical or surgical reasons * Able to give his written informed consent * Affiliation to a social security system * Not participating to another study with psychoactive substance Exclusion Criteria: * Partially-sighted or partially deaf person requiring equipment * Person with brain injury or neurological disease (epileptic, tumoral, vascular, degenerative), diagnoses in personal history or recognized as hereditary * Addiction to psychoactive substance for the last 6 months * Any treatment which could interact with tDCS effects on cortical reactivity (citalopram, amphetamine, L-dopa, sulpiride, pergolide, lorazepam, rivastigmine, dextromethorphan or other N-methyl-D-aspartate (NMDA) receptor antagonists, d-cycloserine, carbamazepine, flunarizine, calcium channel blockers) * Pregnancy and lactation * Any intracephalic metallic material * Person who can't conform to tests instructions * Person suffering from bipolar disorder, chronic or acute delusional disorder * Any circumstances making the person unable to understand the trial features, purposes or consequences

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Conditions

The condition(s) this trial relates to.

post-traumatic stress disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Post traumatic stress disorder

Contacts and locations

Locations

  • CHU Angers

    Angers, 49933, France

  • CHU Nantes

    Nantes, 44000, France

  • CHU Poitiers

    Poitiers, 86021, France

  • CHU Rennes

    Rennes, 35703, France

  • CHU Tours

    Tours, 37044, France

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