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New therapy helps veterans with PTSD rebuild relationships

NCT ID NCT04567680

Symptom relief Sponsor: VA Office of Research and Development Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a type of talk therapy called Acceptance and Commitment Therapy (ACT) to help veterans with PTSD improve their social support and relationships. 107 veterans took part, and the therapy focused on helping them feel less isolated and more connected to family and friends. The goal was to see if this approach works better than standard care for improving social functioning.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

107 people

The number who actually took part.

Started

Mar 2021

Finished

Feb 2025

Lead sponsor

A government agency

The lead sponsor is a US federal agency other than the NIH.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

Children (under 18), adults (18 to 64) and older adults (65 and over)

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Current DSM-5 PTSD diagnosis * Minimum score of 31 on the PCL-5 * Clinically significant difficulties in interpersonal relationships * Competent to provide written informed consent * Ages 18 and older * If being treated with psychoactive medication, no change in drugs or dose for the past 2 months * Willingness to be audio-taped Exclusion Criteria: * Any current or lifetime DSM-5 psychotic disorder * Current or recent (within 1 month of study entry) DSM-5 substance use disorder * Cognitive impairment that would interfere with study participation * Current manic episode * Recent clinically significant suicidality (past 3 months) * Moderate to severe domestic violence (measured by the Conflict Tactics Scale-2) * Current PTSD psychotherapy

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Conditions

The condition(s) this trial relates to.

post-traumatic stress disorder Social Adjustment

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Post-traumatic stress disorder

Contacts and locations

Locations

  • Rocky Mountain Regional VA Medical Center, Aurora, CO

    Aurora, Colorado, 80045, United States

  • VA Bedford HealthCare System, Bedford, MA

    Bedford, Massachusetts, 01730-1114, United States

  • VA Connecticut Healthcare System West Haven Campus, West Haven, CT

    West Haven, Connecticut, 06516-2770, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.