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Could a party drug ease PTSD?

NCT ID NCT06215261

First seen Dec 09, 2025 · Last updated Jun 23, 2026 · Updated 27 times

Summary

This study tested a drug called methylone in 62 adults with severe PTSD. Participants took methylone capsules once a week for 3 to 4 weeks. Researchers measured changes in PTSD and depression symptoms to see if the drug is safe and helpful.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Accel Research

    Maitland, Florida, 32751, United States

  • CNS Healthcare

    Orlando, Florida, 32801, United States

  • Clerkenwell Health

    London, United Kingdom

  • Monarch Mental Health Group

    Melbourne, Victoria, Australia

  • Numinus

    Draper, Utah, 84020, United States

  • Ramsay Clinic Albert Road

    Melbourne, Victoria, 3004, Australia

  • Redbird Research LLC

    Las Vegas, Nevada, 89119, United States

  • Seattle NTC

    Bellevue, Washington, 98004, United States

  • Segal Trials

    Lauderhill, Florida, 33319, United States

  • Sunstone Medical

    Rockville, Maryland, 20850, United States

  • Swinburne University of Technology

    Hawthorn, Victoria, 3122, Australia

  • Uptown Clinical Research

    Chicago, Illinois, 60640, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

methylone

What this could lead to

If it works, this could point toward a new treatment option for people with PTSD.

What could go wrong

This is a small, early-phase trial with only 62 participants. It may not work for everyone, and side effects are possible.

Conditions

The condition(s) this trial relates to.

post-traumatic stress disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.