DIABETES

This study tested an AI-based system called X-Life that gives personalized lifestyle advice to adults with type 2 diabetes. 124 participants used the system along with glucose monitors and activity trackers to see if it improved their blood sugar control compared to standard care…

This study looked at whether adding the antibiotic rifampin to usual treatment can help diabetic patients with serious foot bone infections avoid amputation. Over 800 veterans took part. The goal was to see if the combination works better than standard care alone.

This study tested a 12-week program where people with overweight or obesity, who were already taking weight-loss medications, used a Fitbit and worked with a health coach. The goal was to see if this approach could help them become more active and improve their health. Fifteen pa…

This study tested whether a special health education program that focuses on patient empowerment can help adults with type 2 diabetes better manage their condition. Fifty participants were split into two groups: one received the empowerment-based education, the other standard car…

This pilot study tested a healthy eating and active living program to help people with early Type 2 diabetes achieve remission. 35 adults with diabetes and overweight participated, comparing the program to routine care. The goal was to see if weight loss and blood sugar improveme…

This study tested whether the diabetes pill glyburide works as well as insulin shots for treating gestational diabetes (high blood sugar during pregnancy). Over 900 pregnant women took part. The main goal was to see if the pill could prevent serious newborn problems like large bi…

This study looked at whether a program of diet, aerobic exercise, and balance training could help people with early diabetes or prediabetes who have nerve damage and balance problems. About 61 participants were assigned to either the program or standard care. The goal was to see …

This study tested whether a personalized lifestyle program could help adults with insulin resistance, obesity, diabetes, or related conditions improve their metabolic health. Forty participants first received either nutrition or exercise counseling. Those who didn't improve after…

This study looked at whether treating gum disease (periodontitis) can help people with diabetes better control their blood sugar. 91 adults with both diabetes and gum disease took part. Half received gum treatment right away, while the other half waited. The main goal was to see …

This study tested whether online cooking classes could help people with type 2 diabetes and high body weight improve their diet, blood sugar, and weight. 89 adults took part in virtual culinary medicine sessions. Researchers measured changes in blood sugar (HbA1c), body mass inde…

This study looked at whether community health workers (CHWs) can improve health outcomes for people with chronic conditions like diabetes, high blood pressure, and obesity. Over 10 months, 202 low-income adults from specific zip codes received either CHW support plus standard car…

This early-phase study tested whether a protein called apelin can improve how the body uses insulin in people with type 2 diabetes. Nine overweight adults with type 2 diabetes received apelin to measure changes in their body's ability to process sugar. The goal was to see if apel…

This study tested a new device used during an endoscopy to regenerate the lining of the first part of the small intestine in people with type 2 diabetes. The goal was to see if the procedure is safe and could help improve blood sugar control. Twenty adults with diabetes not well …

This study tested whether a program that combines job support with health coaching can reduce risks for chronic diseases like diabetes and high blood pressure in unemployed people. 455 participants received help finding work and managing stress. Researchers measured changes in we…

This study tested whether bringing HIV and chronic disease care into the community and linking it with microfinance groups helps people with HIV stay in care and keep the virus under control. About 1,200 adults in rural Kenya took part. The goal was to see if this combined approa…

This study tested a fully automated system that delivers both insulin and glucagon to manage blood sugar in adults with type 1 diabetes. Over 12 months, 243 participants used either this dual-hormone system or standard care. The goal was to see if the new system helps people spen…

This study tested two drugs—hydralazine-ISDN and metformin—in 1100 adults with chronic heart failure and reduced heart function. Some participants also had diabetes or were at risk for it. The goal was to see if these drugs could lower the chance of death or hospital stays due to…

This study tested a program to help South Asian adults with uncontrolled diabetes lower their blood sugar levels. The program included health coaching, referrals to community resources, and better coordination between patients and their healthcare team. 859 participants took part…

This pilot study tested a closed-loop system that automatically adjusts insulin delivery for people with type 1 diabetes. Five adults who already use an insulin pump and continuous glucose monitor took part. The goal was to see if the system works reliably and helps keep blood su…

This pilot study tested whether people with type 2 diabetes and early kidney disease can take part in a clinical trial from home. Twelve participants collected their own urine, blood, and blood pressure readings remotely. They took empagliflozin first, and based on their response…

This study tested whether lifestyle coaching delivered through a hospital's online patient portal helps adults maintain weight loss and prevent diabetes. 269 adults who had already lost at least 5% of their body weight took part. Some received coaching from regular clinic staff, …

This study tested a program called Family Check-Up Heart, which adds heart-health coaching to home visits for new moms and their babies. About 117 mothers who had Medicaid and lived in Allegheny County took part. The goal was to see if the program helped moms keep a healthy weigh…

This study looked at whether getting blood sugar under control for a short time before major abdominal surgery can lower the chance of problems or death. It included 53 adults with uncontrolled diabetes (HbA1c of 7.5% or higher) who were scheduled for surgery lasting over 2 hours…

This study tested a personalized lifestyle program for 232 overweight or obese Hispanic women during and after pregnancy. The goal was to help them gain a healthy amount of weight during pregnancy, lose weight after birth, and improve blood sugar and other health markers. The pro…

This study tested a program where community health workers helped young adults (ages 18-35) from underrepresented minority groups with type 1 diabetes start and continue using diabetes technology like continuous glucose monitors and insulin pumps. Over 9 months, 119 participants …

This early-stage study tested an experimental drug called CT-388 in 129 overweight or obese adults, some with type 2 diabetes. The goal was to check safety and how the drug affects body weight and blood sugar. Participants received either the drug or a placebo as a shot under the…

This study tested a new device that measures blood sugar without needing a finger prick. It compared the device's readings to standard blood tests in 40 adults, including healthy people, those with prediabetes, and those with type 2 diabetes. The goal was to see if the non-invasi…

This study tested a new automated screening tool called OPTDR01 to detect diabetic retinopathy, a leading cause of vision loss. The tool is designed for use in primary care clinics to make screening more accessible, especially for underserved groups. Researchers enrolled 300 adul…

This study checked how well the LS-9 blood glucose monitor measures blood sugar levels in 219 people with diabetes. The goal was to see if it meets international accuracy standards. Participants included those with low, normal, and high blood sugar levels.

This study tested a program that gives healthy food incentives to adults at risk for diabetes. The goal was to help them stick with a diabetes prevention program and make lasting lifestyle changes. 61 participants were enrolled to see if the program improved attendance and health…

This study looked at whether foot-ankle exercises or walking exercises can help people with type 2 diabetes who have foot nerve problems. 375 adults with diabetes did either foot exercises, walking, or received standard care for 12 weeks. Researchers measured foot sensation, stre…

This study tested a program that sends text reminders and uses social support and game-like features to encourage people with chronic kidney disease, diabetes, and high blood pressure to check their blood pressure regularly. 70 adults from a University of Pennsylvania kidney clin…

This study looked at whether quercetin, a compound found in foods like apples and onions, changes how the body absorbs sugar. Researchers gave 24 obese adults, some with type 2 diabetes, either quercetin or a placebo during a sugar-drink test. They measured blood sugar levels to …

This study tested a mobile health program designed to support family caregivers who look after someone with both dementia and diabetes. Sixty caregivers used the program for three months. The goal was to reduce their burden and improve their social support. The program provided g…

This pilot study tested a new word game-based workbook to help people with diabetes learn how to manage their condition. 25 participants completed the workbook during clinic visits or at home, playing games that taught diabetes terms and meal planning. The goal was to see if this…

This study tested whether the diabetes drug acarbose, adjusted using a continuous glucose monitor, could reduce nerve pain in adults with type 2 diabetes. 170 participants with painful diabetic neuropathy and high blood sugar swings took either acarbose or a placebo for 4 weeks. …

This study tested whether a foot-ankle exercise program could help adults with type 2 diabetes manage nerve pain, stress, and quality of life better than walking or standard care. 108 people took part for 12 weeks, doing either foot-ankle exercises, walking, or receiving educatio…

This study tested a personalized home exercise program for 34 cancer survivors who also had diabetes or high blood pressure. Participants chose from four exercise options (like walking or yoga) and used a wearable device to track their heart rate. The goal was to see if the progr…

This study tested a new method called inforatio to help heal diabetic foot ulcers. The technique involves making small cuts in the wound to trigger the body's natural healing response. 100 adults with diabetes took part. The main goal was to see if the ulcers healed completely.

This study looked at 103 diabetic adults starting chemotherapy to see if a continuous glucose monitor (Freestyle Libre) could better track dangerous blood sugar highs and lows. Researchers wanted to find out if this device could help doctors manage diabetes more closely during ca…

This study measured levels of a recently discovered hormone called 26RFa in 62 women. Researchers compared obese women with or without type 2 diabetes to healthy-weight volunteers. They also checked how the hormone changed after weight-loss surgery (sleeve gastrectomy). The goal …

This study looked at how lifestyle changes like diet and exercise affect blood sugar in 61 adults with diabetes. Researchers used advanced tests to study genes, proteins, and gut bacteria. The goal was to find the key biological pathways that help control glucose and build a tool…

This study looked at how two diabetes medications—metformin and an experimental drug called HRS-7535—affect each other's levels in the body. It involved 18 healthy men aged 18 to 50. The goal was purely to measure drug concentrations and safety, not to treat any disease.

This study aimed to find out how often low blood sugar (hypoglycemia) happens in older adults (over 64) with diabetes who live in long-term care facilities. Researchers used a continuous glucose monitor (CGM) worn for 10 days to track blood sugar levels in 86 participants. The go…

This study looked at how vitamin E is absorbed and used by women who are normal weight, overweight, or have type 2 diabetes. Researchers measured vitamin E levels in blood and tissues after giving different doses and meals. The goal was to learn more about vitamin E needs in wome…

This study analyzed health records from over 740,000 older adults with diabetes to see if certain diabetes medications, like semaglutide, are linked to a lower risk of developing dementia or Alzheimer's disease. Researchers compared people taking semaglutide to those on other dia…

This study looked for rare, single-gene causes of insulin-dependent diabetes in 127 participants. Researchers examined patients' genes, medical histories, and family members to identify new forms of diabetes. The goal was to better understand these genetic subtypes, not to test a…

This study looked at whether online referrals from doctors to the WIC food program help more pregnant women enroll. About 240 pregnant women on public insurance or uninsured took part. Some got usual care, others got a direct referral or extra dietitian support. The goal was to s…

This study checked whether acetaminophen (Tylenol) interferes with the Biolinq continuous glucose monitor, a device that measures blood sugar through the skin. Thirty-one adults with diabetes wore the Biolinq sensor and a standard monitor for three days. On the third day, they to…

This study tested a text-message program for adults with diabetes visiting the emergency department. The program sent educational materials and resource referrals to help patients manage their condition. Researchers measured changes in diabetes knowledge, distress, and self-care.…

This study tested a new wearable sensor (Biolinq) that measures blood sugar continuously for up to 5 days in 247 adults with diabetes. Participants wore the sensor and a standard monitor, and compared readings with lab tests. The goal was to see if the new sensor is safe and accu…

This study looked at whether viral infections in pregnant women with diabetes might increase the chance of their babies being born with heart defects. Researchers analyzed blood and stool samples from 114 women to detect viruses and immune responses. The goal was to gather initia…

This study looked at how different types of diets affect the number of calories people burn and their risk for diseases like diabetes and heart problems. 234 adults who were overweight or obese took part. Researchers measured their total energy use and resting metabolism to under…

This study looked at 120 people having hand or wrist surgery to see if kidney failure or diabetes affects how long a nerve block lasts. Researchers measured the time it took for feeling to return after the block. The goal was to understand how these metabolic conditions change th…

This study looked at how a class of diabetes drugs called SGLT2 inhibitors affect kidney function in people with chronic kidney disease (CKD). Researchers compared 60 patients with and without diabetes to see if the drugs changed their estimated glomerular filtration rate (eGFR),…

This study looked at over 30,000 adults admitted to hospitals in Maryland to understand why some patients wait in the emergency room even after being admitted (called boarding). Researchers wanted to find out which patients are more likely to board, how boarding increases healthc…

This study looked at 200 patients who had surgery to clear blocked neck arteries. Researchers checked the removed plaque for bacteria and tracked whether certain germs were linked to later problems like stroke or re-blockage. The goal was to learn which bacteria might be risky, n…

This study looked at how many calories people burn through physical activity and whether that affects body weight and diabetes risk. Researchers followed 2,506 Black adults from Ghana, South Africa, Seychelles, Jamaica, and the United States for two years. They used special water…

This study looked at whether replacing sitting time with standing and walking can improve daily blood sugar levels in South Asian adults who are overweight or obese. Eighteen participants changed their daily routines to sit less and move more. The results showed that this simple …

This study looked at how Mexican-American families discuss their risk for diabetes, heart disease, breast cancer, and colon cancer. Researchers interviewed 498 adults from Houston-area households to understand how culture and family relationships help or hinder health conversatio…

This pilot study tested whether combining health information technology with practice facilitation (coaching for clinic staff) could increase the number of diabetes patients referred to diabetes self-management education and support (DSMES). The study involved 22 clinics and meas…

This study looked at how often dangerously low blood sugar (hypoglycemia) occurs in elderly diabetic patients living in nursing homes. Researchers monitored 29 residents using continuous glucose monitors and compared that to standard finger-prick tests. The goal was to find hidde…

This study looked at 146 healthy women of African, African-American, and white backgrounds to see if race affects how we screen for diabetes and heart disease. Participants had blood tests, body fat measurements, and meal tests over four visits. The goal was to find the best scre…

This study looked at whether mothers can help their families adopt healthier habits by learning about their family health history. About 310 adults took part, completing surveys and using a Family Health Package that explained risks for diabetes, cancer, and heart disease. The go…

This study followed 514 people with stable coronary artery disease for 18 months to see if how their bodies handle triglycerides (a type of fat) after a meal could predict future heart problems. Researchers also looked at blood sugar control and other health markers. The goal was…

This study tested a new AI system called X Life that gives personalized health tips to people with type 2 diabetes or prediabetes. The system uses data from continuous glucose monitors, activity trackers, and sleep sensors to offer tailored advice. Twenty participants used the sy…

This study looked at whether taking short, regular walks during long periods of sitting can help lower blood sugar and cholesterol after meals—key risk factors for Type 2 diabetes and heart disease. Researchers compared normal-weight and overweight/obese South Asian adults, a gro…

This study looked at how family members talk about genetic health risks like sickle cell, diabetes, cancer, and heart disease. Over 1,000 adults completed surveys or interviews about their family health history and support. The goal was to understand how sharing this information …