Could a simple antibiotic spare diabetics from losing a foot?
NCT ID NCT03012529
First seen Jan 11, 2026 · Last updated Apr 25, 2026 · Updated 24 times
Summary
This study looked at whether adding the antibiotic rifampin to usual treatment can prevent foot or leg amputations in people with diabetes who have a bone infection (osteomyelitis). Over 800 veterans took part. The goal was to see if the combination works better than standard antibiotics alone to save limbs and improve outcomes.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Atlanta VA Medical and Rehab Center, Decatur, GA
Decatur, Georgia, 30033, United States
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Bay Pines VA Healthcare System, Pay Pines, FL
Bay Pines, Florida, 33744-0000, United States
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Cincinnati VA Medical Center, Cincinnati, OH
Cincinnati, Ohio, 45220, United States
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Dayton VA Medical Center, Dayton, OH
Dayton, Ohio, 45428, United States
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James A. Haley Veterans' Hospital, Tampa, FL
Tampa, Florida, 33612, United States
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James J. Peters VA Medical Center, Bronx, NY
The Bronx, New York, 10468-3904, United States
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Louis Stokes VA Medical Center, Cleveland, OH
Cleveland, Ohio, 44106-1702, United States
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Miami VA Healthcare System, Miami, FL
Miami, Florida, 33125, United States
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Michael E. DeBakey VA Medical Center, Houston, TX
Houston, Texas, 77030, United States
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Minneapolis VA Health Care System, Minneapolis, MN
Minneapolis, Minnesota, 55417, United States
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North Florida/South Georgia Veterans Health System, Gainesville, FL
Gainesville, Florida, 32608-1135, United States
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Oklahoma City VA Medical Center, Oklahoma City, OK
Oklahoma City, Oklahoma, 73104, United States
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Phoenix VA Health Care System, Phoenix, AZ
Phoenix, Arizona, 85012, United States
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Rocky Mountain Regional VA Medical Center, Aurora, CO
Aurora, Colorado, 80045-7211, United States
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Salem VA Medical Center, Salem, VA
Salem, Virginia, 24153-6404, United States
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Salisbury W.G. (Bill) Hefner VA Medical Center, Salisbury, NC
Salisbury, North Carolina, 28144, United States
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South Texas Health Care System, San Antonio, TX
San Antonio, Texas, 78229, United States
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St. Louis VA Medical Center John Cochran Division, St. Louis, MO
St Louis, Missouri, 63106, United States
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Tennessee Valley Healthcare System Nashville Campus, Nashville, TN
Nashville, Tennessee, 37212-2637, United States
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VA Ann Arbor Healthcare System, Ann Arbor, MI
Ann Arbor, Michigan, 48105-2303, United States
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VA Greater Los Angeles Healthcare System, West Los Angeles, CA
West Los Angeles, California, 90073, United States
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VA Loma Linda Healthcare System, Loma Linda, CA
Loma Linda, California, 92357-1000, United States
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VA Long Beach Healthcare System, Long Beach, CA
Long Beach, California, 90822, United States
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VA North Texas Health Care System Dallas VA Medical Center, Dallas, TX
Dallas, Texas, 75216-7167, United States
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VA Northern California Health Care System, Mather, CA
Sacramento, California, 95655, United States
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VA Palo Alto Health Care System, Palo Alto, CA
Palo Alto, California, 94304-1207, United States
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VA Portland Health Care System, Portland, OR
Portland, Oregon, 97207-2964, United States
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VA Salt Lake City Health Care System, Salt Lake City, UT
Salt Lake City, Utah, 84148-0001, United States
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Washington DC VA Medical Center, Washington, DC
Washington D.C., District of Columbia, 20422-0001, United States
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William S. Middleton Memorial Veterans Hospital, Madison, WI
Madison, Wisconsin, 53705-2254, United States
Conditions
Explore the condition pages connected to this study.