POSTOPERATIVE PAIN
Clinical trials for POSTOPERATIVE PAIN explained in plain language.
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Nerve block may ease neck surgery pain, cut opioid use
Symptom relief OngoingThis study tests whether an ultrasound-guided nerve block (superficial cervical plexus block) can reduce pain after neck surgery. Sixty adults having elective neck surgery under general anesthesia will be randomly assigned to receive the block or not. The main goal is to see if t…
Matched conditions: POSTOPERATIVE PAIN
Phase: PHASE4 • Sponsor: Sohag University • Aim: Symptom relief
Last updated May 17, 2026 04:29 UTC
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New pain relief combo for brain surgery patients shows promise
Symptom relief TerminatedThis study looks at whether adding flurbiprofen axetil to a standard numbing medicine (ropivacaine) can better control pain after brain surgery. About 216 adults having planned brain surgery will receive the combination or standard care. The goal is to see if patients need less a…
Matched conditions: POSTOPERATIVE PAIN
Phase: NA • Sponsor: Beijing Tiantan Hospital • Aim: Symptom relief
Last updated May 17, 2026 04:27 UTC
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Which nerve block eases back surgery pain best?
Symptom relief OngoingThis study compares two types of nerve blocks (QLB and RLB) for pain after lumbar disc surgery. About 84 adults having elective back surgery will receive one of the blocks. Researchers will measure pain scores, opioid use, and patient satisfaction to see which block works better.
Matched conditions: POSTOPERATIVE PAIN
Phase: NA • Sponsor: Kocaeli University • Aim: Symptom relief
Last updated May 17, 2026 04:26 UTC
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New study aims to cut opioid use after nose surgery
Symptom relief ENROLLING_BY_INVITATIONThis study looks at whether giving extra numbing medication during nose surgery can help patients use fewer strong opioid pain pills afterward. About 50 adults having nose surgery at two military hospitals will take part. Half will get the extra numbing medicine, and half will no…
Matched conditions: POSTOPERATIVE PAIN
Phase: PHASE3 • Sponsor: United States Naval Medical Center, Portsmouth • Aim: Symptom relief
Last updated May 17, 2026 04:25 UTC
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New study tests which nerve block cuts pain pills after hernia repair
Symptom relief ENROLLING_BY_INVITATIONThis study compares two ultrasound-guided pain blocks (TAP block and quadratus lumborum block) given before open inguinal hernia repair under spinal anesthesia. 70 adults aged 18-65 will be randomly assigned to one block, and their pain scores and opioid use will be tracked for 2…
Matched conditions: POSTOPERATIVE PAIN
Phase: NA • Sponsor: Hitit University • Aim: Symptom relief
Last updated May 17, 2026 04:17 UTC
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New pain block could cut opioid use after neck surgery
Symptom relief OngoingThis study looks at whether a specific nerve block can lower pain and the need for painkillers after cervical disc surgery. About 40 adults having this neck surgery will receive either the nerve block or standard care. The goal is to see if the block leads to better pain control …
Matched conditions: POSTOPERATIVE PAIN
Phase: NA • Sponsor: Cumhuriyet University • Aim: Symptom relief
Last updated May 17, 2026 04:17 UTC
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New combo could keep you Pain-Free longer after surgery
Symptom relief OngoingThis study tests whether adding a second drug (dexmedetomidine) to the standard nerve block medication (dexamethasone) can make pain relief last longer after shoulder, foot, or ankle surgery. About 100 adults will receive either the combo or the standard block, then report their …
Matched conditions: POSTOPERATIVE PAIN
Phase: PHASE1, PHASE2 • Sponsor: University of Arizona • Aim: Symptom relief
Last updated May 17, 2026 04:16 UTC
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New nerve block technique may slash opioid use after major abdominal surgery
Symptom relief OngoingThis study tests whether a special nerve block (erector spinae plane block) can lower the need for strong painkillers after open abdominal surgery. About 46 adults having surgery under general anesthesia will be randomly assigned to get the block or not. The goal is to see if the…
Matched conditions: POSTOPERATIVE PAIN
Phase: NA • Sponsor: Fatima Memorial Hospital • Aim: Symptom relief
Last updated May 17, 2026 04:13 UTC
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Which drug calms nerves before hemorrhoid surgery? new study investigates
Symptom relief OngoingThis study tests two medications, dexmedetomidine and tramadol, given before hemorrhoid surgery to see which one better reduces anxiety and pain. 90 adults undergoing the procedure will be randomly assigned to receive one of the drugs, and their anxiety levels, pain scores, and v…
Matched conditions: POSTOPERATIVE PAIN
Phase: NA • Sponsor: Yuzuncu Yil University • Aim: Symptom relief
Last updated May 17, 2026 04:12 UTC
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Cartoon cure for surgery jitters: video calms kids before tonsil removal
Symptom relief OngoingThis study looks at whether showing children a video before their tonsil surgery can lower their fear, anxiety, and pain. About 60 kids aged 4 to 10 will watch the video and then report how they feel using simple scales. The goal is to make the surgery experience less scary and m…
Matched conditions: POSTOPERATIVE PAIN
Phase: NA • Sponsor: Istanbul University - Cerrahpasa • Aim: Symptom relief
Last updated May 17, 2026 04:12 UTC
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Which pain block works best for abdominal surgery recovery?
Symptom relief OngoingThis study compares two types of nerve blocks—subcostal TAP block and rectus sheath block—for controlling pain after abdominal surgery with a midline cut. Sixty adults having this surgery will receive one of the two blocks, and researchers will measure their pain scores and how m…
Matched conditions: POSTOPERATIVE PAIN
Phase: NA • Sponsor: Cumhuriyet University • Aim: Symptom relief
Last updated May 15, 2026 11:57 UTC
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Which nerve block eases hip fracture pain best? new study aims to find out
Symptom relief OngoingThis study compares two types of nerve blocks (pericapsular nerve block and anterior quadratus lumborum block) to see which one better reduces pain during spinal anesthesia positioning and after surgery for hip fractures. Researchers will enroll 64 adults aged 30-85 undergoing el…
Matched conditions: POSTOPERATIVE PAIN
Sponsor: Erzincan University • Aim: Symptom relief
Last updated May 15, 2026 11:57 UTC
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Wisdom tooth pain relief: steroid injection shows promise
Symptom relief OngoingThis study looks at whether a single injection of dexamethasone, a steroid, can reduce pain after surgical removal of impacted wisdom teeth. About 70 adults will be split into two groups: one gets standard numbing medicine, the other gets an extra steroid shot after surgery. Pain…
Matched conditions: POSTOPERATIVE PAIN
Phase: NA • Sponsor: 28 Military Dental Centre Lahore • Aim: Symptom relief
Last updated May 15, 2026 11:56 UTC
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New pain block may match epidural for surgery recovery
Symptom relief OngoingThis study looks at two ways to manage pain after gynecologic surgery: the EXORA block and epidural analgesia. Researchers want to see which method helps patients recover better and feel less pain. About 60 adults having planned gynecologic surgery will take part, and their recov…
Matched conditions: POSTOPERATIVE PAIN
Phase: NA • Sponsor: Bursa Yuksek Ihtisas Training and Research Hospital • Aim: Symptom relief
Last updated May 15, 2026 11:53 UTC
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Nose job recovery: do steroids cut pain and swelling?
Symptom relief TerminatedThis study aimed to see if taking oral steroids after nose surgery (rhinoplasty) reduces pain, nausea, swelling, and bruising. It planned to include adults having their first nose surgery, but was withdrawn before any participants enrolled. The goal was to improve patient comfort…
Matched conditions: POSTOPERATIVE PAIN
Phase: PHASE4 • Sponsor: Vanderbilt University Medical Center • Aim: Symptom relief
Last updated May 14, 2026 12:06 UTC
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New recovery plan aims to cut painkiller use in kidney transplants
Symptom relief ENROLLING_BY_INVITATIONThis study tests whether an Enhanced Recovery After Surgery (ERAS) protocol can lower the need for strong painkillers after a live donor kidney transplant. About 60 adult patients will follow a special plan that includes a pre-surgery drink, Tylenol, gabapentin, a numbing injecti…
Matched conditions: POSTOPERATIVE PAIN
Phase: PHASE4 • Sponsor: Baylor Research Institute • Aim: Symptom relief
Last updated May 14, 2026 12:06 UTC
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New pain block for shoulder surgery may spare breathing muscle
Symptom relief OngoingThis study compares two types of nerve blocks given before shoulder surgery to control pain and prevent temporary paralysis of the diaphragm, the main breathing muscle. Thirty adults having arthroscopic shoulder surgery will receive one of the two blocks. The goal is to see which…
Matched conditions: POSTOPERATIVE PAIN
Phase: NA • Sponsor: Cumhuriyet University • Aim: Symptom relief
Last updated May 14, 2026 12:04 UTC
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New nerve block combo may offer safer pain relief for broken collarbone surgery
Symptom relief OngoingThis study tests two ways to numb the shoulder area for collarbone fracture surgery. One method (SCB-ISB) can sometimes cause breathing problems. The other (SCB-CPB) aims to provide the same pain relief but with fewer side effects. 34 adults having collarbone surgery will be rand…
Matched conditions: POSTOPERATIVE PAIN
Phase: NA • Sponsor: Udayana University • Aim: Symptom relief
Last updated May 14, 2026 12:03 UTC
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New pain block study aims to ease recovery after belly surgery
Symptom relief OngoingThis study compares two types of nerve blocks to control pain after abdominal surgery. Sixty adults having surgery through a midline belly cut will receive either a modified thoracoabdominal nerve block or a rectus sheath block. The goal is to see which method provides better pai…
Matched conditions: POSTOPERATIVE PAIN
Phase: NA • Sponsor: Cumhuriyet University • Aim: Symptom relief
Last updated May 14, 2026 12:02 UTC
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New pain block may beat standard shot for gallbladder surgery recovery
Symptom relief OngoingThis study compares two pain relief methods for people having their gallbladder removed by keyhole surgery. One method is a nerve block (serratus-intercostal plane block), the other is injecting pain medicine into the surgical cuts (port infiltration). 128 adults will be randomly…
Matched conditions: POSTOPERATIVE PAIN
Phase: NA • Sponsor: Hospital del Rio Hortega • Aim: Symptom relief
Last updated May 12, 2026 13:43 UTC
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Pain relief study pulled before it even started
Symptom relief TerminatedThis study aimed to see if injecting Exparel (a long-lasting painkiller) into the vaginal cuff before a minimally invasive hysterectomy could reduce pain after surgery. It was designed for adults having robotic or laparoscopic hysterectomy for non-cancer reasons. However, the stu…
Matched conditions: POSTOPERATIVE PAIN
Phase: PHASE4 • Sponsor: Olivia Sher • Aim: Symptom relief
Last updated May 12, 2026 13:39 UTC
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Gentler hemorrhoid surgery aims to cut pain, but study never started
Symptom relief TerminatedThis study planned to compare a less invasive version of open hemorrhoid surgery with the standard approach in adults with grade III hemorrhoids. The goal was to see if the gentler method causes less pain after the operation. However, the study was withdrawn before enrolling any …
Matched conditions: POSTOPERATIVE PAIN
Phase: NA • Sponsor: Hospital Son Llatzer • Aim: Symptom relief
Last updated May 11, 2026 20:51 UTC
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New pain block could reduce opioid use after kidney stone surgery
Symptom relief OngoingThis study looks at whether a special nerve block called a quadro-iliac plane block can reduce pain and the need for painkillers after kidney stone surgery. About 60 adults having this surgery will be included. The goal is to see if this block makes recovery more comfortable and …
Matched conditions: POSTOPERATIVE PAIN
Phase: NA • Sponsor: Cumhuriyet University • Aim: Symptom relief
Last updated May 11, 2026 20:49 UTC
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Nerve block may cut pain and hospital time after back surgery
Symptom relief OngoingThis study looks at whether a specific nerve block (called ESPB) can help control pain after surgery for a slipped disc in the lower back. The goal is to see if it reduces the need for strong painkillers, helps patients get moving sooner, and shortens their hospital stay. About 7…
Matched conditions: POSTOPERATIVE PAIN
Sponsor: Başakşehir Çam & Sakura City Hospital • Aim: Symptom relief
Last updated May 07, 2026 18:40 UTC
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Pre-Surgery steroid may cut wisdom tooth recovery woes
Symptom relief OngoingThis study looked at whether giving a single dose of long-acting corticosteroids before removing impacted wisdom teeth can reduce pain, facial swelling, and trouble opening the mouth after surgery. Sixty adults aged 18 to 35 were randomly assigned to receive either the steroid or…
Matched conditions: POSTOPERATIVE PAIN
Phase: NA • Sponsor: Al Salam University • Aim: Symptom relief
Last updated May 06, 2026 16:14 UTC
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Hernia patients may ditch opioids without extra pain
Symptom relief OngoingThis study tests whether giving no opioids after routine inguinal hernia repair works as well as giving a few opioid pills. About 900 adults having hernia surgery will either receive no opioids or a small supply (5 pills). The main goal is to see if the no-opioid group needs fewe…
Matched conditions: POSTOPERATIVE PAIN
Phase: PHASE4 • Sponsor: Clayton Petro • Aim: Symptom relief
Last updated May 05, 2026 11:55 UTC
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New study aims to cut opioid use after breast reduction with targeted nerve blocks
Symptom relief OngoingThis study compares two types of nerve blocks (serratus plane block and rhomboid intercostal plane block) to see which provides better pain relief after breast reduction surgery. Ninety women undergoing the surgery will receive one of the two blocks before anesthesia. The main go…
Matched conditions: POSTOPERATIVE PAIN
Phase: NA • Sponsor: Konul Karaja • Aim: Symptom relief
Last updated May 01, 2026 16:00 UTC
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Scientists measure pain threshold under opioid influence
Knowledge-focused ENROLLING_BY_INVITATIONThis study looks at how the opioid remifentanil affects pain sensitivity in 40 adults before surgery. Researchers will measure pain threshold using a pressure device at different drug levels. The goal is to better understand pain control and potentially improve anesthesia practic…
Matched conditions: POSTOPERATIVE PAIN
Phase: NA • Sponsor: Université Libre de Bruxelles • Aim: Knowledge-focused
Last updated May 17, 2026 04:12 UTC
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Blood markers may predict dental numbing failure
Knowledge-focused OngoingThis study looks at whether certain signs of inflammation in the blood can predict how well dental numbing works and how much pain people feel after treatment. About 150 adults with tooth pain will have their blood tested and their anesthesia success measured. The goal is to help…
Matched conditions: POSTOPERATIVE PAIN
Sponsor: KEZBAN MELTEM ÇOLAK • Aim: Knowledge-focused
Last updated May 15, 2026 11:56 UTC
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Light therapy after surgery: does it really help?
Knowledge-focused ENROLLING_BY_INVITATIONThis study tracks 300 adults who get light therapy as part of their standard care after elective plastic surgery. Researchers will measure pain, swelling, bruising, and patient satisfaction over time. The goal is to describe recovery patterns, not to test a new treatment.
Matched conditions: POSTOPERATIVE PAIN
Sponsor: Elixir MD Inc • Aim: Knowledge-focused
Last updated May 15, 2026 11:55 UTC
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Gene study aims to make pain relief safer for kids after surgery
Knowledge-focused OngoingThis study looks at how a child's genes affect their response to morphine after surgery. By analyzing DNA from 1,200 children having their tonsils removed, researchers hope to predict who will have serious side effects or poor pain relief. The goal is to personalize pain medicine…
Matched conditions: POSTOPERATIVE PAIN
Sponsor: Senthil Sadhasivam • Aim: Knowledge-focused
Last updated May 14, 2026 12:01 UTC