Blood markers may predict why your dental numbing fails

NCT ID NCT07163065

Ongoing Knowledge-focused Sponsor: KEZBAN MELTEM ÇOLAK Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study looks at whether certain inflammation markers in the blood can predict how well dental numbing shots work and how much pain people feel after treatment. Researchers will analyze blood samples from 150 adults with tooth inflammation (irreversible pulpitis) and compare them to anesthesia success and post-op pain. The goal is to help dentists identify patients who may need extra numbing or pain relief.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could help dentists predict which patients might have a failed numbing shot and improve pain management for dental procedures.
What could go wrong: This is an observational study, not a treatment trial. It only looks for links between blood markers and anesthesia success, so it won't directly change care yet.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative pulpitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DENTAL ANESTHESIA COMPLICATIONS INFERIOR ALVEOLAR NERVE BLOCK FAILURE INFLAMMATION BIOMARKERS POSTOPERATIVE PAIN

Contacts and locations

Locations

Atatürk University Faculty of Dentistry, Department of Endodontics

Erzurum, Erzurum, 25240, Turkey (Türkiye)

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