New shot aims to slash post-surgery pain and opioid use

NCT ID NCT07222748

Recruiting now Symptom relief Sponsor: TLC Biopharmaceuticals, Inc. Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated Apr 24, 2026 · Updated 29 times

Summary

This study tests an experimental pain-relief injection called TLC590 in 300 adults having bunionectomy (foot bone surgery). The goal is to see if it reduces pain for 3 days after surgery and helps people avoid stronger opioid painkillers. Participants are randomly assigned to get TLC590, a standard painkiller, or a placebo (salt water) injected into the surgical site.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Clinical Pharmacology of Miami
NOT_YET_RECRUITING

Miami, Florida, 33172, United States
Endeavor Clinical Trials
NOT_YET_RECRUITING

San Antonio, Texas, 78240, United States
First Surgical Hospital
RECRUITING

Bellaire, Texas, 77401, United States
Memorial Hermann Village
RECRUITING

Houston, Texas, 77043, United States

Conditions

Explore the condition pages connected to this study.

POSTOPERATIVE PAIN