New injection could cut opioid use after bunion surgery

NCT ID NCT07222748

First seen Jun 27, 2026 · Last updated Jul 02, 2026 · Updated 1 time

Summary

This study tests a new medicine called TLC590 for pain after bunionectomy (foot bone surgery). About 300 adults will receive either TLC590, a standard painkiller, or a placebo. The goal is to see if TLC590 reduces pain and the need for opioid painkillers in the first 72 hours after surgery.

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Conditions

The condition(s) this trial relates to.

Bunion Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Clinical Pharmacology of Miami

    Miami, Florida, 33172, United States

  • Endeavor Clinical Trials

    San Antonio, Texas, 78240, United States

  • First Surgical Hospital

    Bellaire, Texas, 77401, United States

  • Memorial Hermann Village

    Houston, Texas, 77043, United States

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