Hormone clues to IVF pain: estrogen may predict discomfort after egg retrieval

NCT ID NCT03105518

First seen Jul 29, 2026 · Last updated Jul 30, 2026 · Updated 1 time

Summary

This study investigates whether a woman's estrogen levels can predict how much pain she feels after egg retrieval during IVF. Researchers will measure pain scores in 100 women undergoing the procedure with standard anesthesia. The goal is to see if higher estrogen is linked to more discomfort, which could help personalize pain relief in the future.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
fentanyl, acetaminophen, and oxycodone
What this could lead to
If estrogen levels are linked to pain, doctors may tailor pain management for women undergoing egg retrieval.
What could go wrong
This is a small, single-center study. The link between estrogen and pain may not be strong enough to change practice.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02115, United States

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