New scalp injection could ease pain after brain surgery
NCT ID NCT05624359
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether adding flurbiprofen axetil to a standard numbing medicine (ropivacaine) injected into the scalp before brain surgery can reduce pain afterward. About 216 adults having brain surgery will be randomly assigned to receive either the combination or the numbing medicine alone. The main goal is to see if the combination lowers the need for additional pain medicine through a patient-controlled pump over 48 hours.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- flurbiprofen axetil plus ropivacaine
- What this could lead to
- If it works, this could offer a better way to manage pain after brain surgery, reducing the need for strong opioids.
- What could go wrong
- This is a small, suspended early-phase trial. The added benefit over standard care may be small, and results may not apply to all patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Beijing Tiantan Hospital
Beijing, China
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