OSTEOPOROSIS
Clinical trials for OSTEOPOROSIS explained in plain language.
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Shake and inject: new combo fights bone loss in spinal injury patients
Disease control CompletedThis study tested whether a daily injection (teriparatide) and/or daily vibration therapy could help rebuild bone in people with long-term spinal cord injuries who cannot walk. Sixty participants were assigned to receive either the drug, the vibration, both, or neither for one ye…
Matched conditions: OSTEOPOROSIS
Phase: PHASE2 • Sponsor: Thomas J. Schnitzer • Aim: Disease control
Last updated Apr 01, 2026 14:43 UTC
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Do arthritis drugs protect bones after menopause?
Disease control CompletedThis study looked at how bone density changes over time in postmenopausal women with rheumatoid arthritis, a condition that increases fracture risk. Researchers followed 82 women to see how different combinations of arthritis medications and bone-strengthening treatments affected…
Matched conditions: OSTEOPOROSIS
Sponsor: Istanbul University - Cerrahpasa • Aim: Disease control
Last updated Mar 30, 2026 14:33 UTC
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Can a single infusion save bones after spinal injury?
Disease control CompletedThis study tested whether a medication called zoledronic acid could prevent the severe bone loss that often happens after a spinal cord injury. For two years, researchers compared the drug to a placebo in 60 adults who had a recent injury and could not walk independently. The goa…
Matched conditions: OSTEOPOROSIS
Phase: PHASE2 • Sponsor: Northwestern University • Aim: Disease control
Last updated Mar 30, 2026 14:32 UTC
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New hope for stronger bones after spinal injury
Disease control CompletedThis small, completed pilot study tested a two-step drug treatment to control bone loss in women with chronic spinal cord injury and osteoporosis. Twelve participants received monthly injections of romosozumab for one year to build bone, followed by a year of weekly alendronate p…
Matched conditions: OSTEOPOROSIS
Phase: PHASE2 • Sponsor: Northwestern University • Aim: Disease control
Last updated Mar 30, 2026 14:29 UTC
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Bone drug switch tested to stop dangerous bone loss
Disease control CompletedThis study looked at whether switching patients from long-term denosumab treatment to other bone-strengthening drugs (alendronate or zoledronate) could prevent rapid bone loss. It involved 44 postmenopausal women and men over 50 who had been on denosumab for at least three years.…
Matched conditions: OSTEOPOROSIS
Phase: PHASE4 • Sponsor: National Taiwan University Hospital • Aim: Disease control
Last updated Mar 27, 2026 12:41 UTC
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New program fights frailty in seniors with weak bones and muscles
Disease control CompletedThis study tested whether a 12-week program of specific exercises and a nutritional supplement could help older adults who have both osteoporosis (weak bones) and sarcopenia (age-related muscle loss). Thirteen participants were split into two groups: one started the program right…
Matched conditions: OSTEOPOROSIS
Phase: NA • Sponsor: Kowloon Hospital, Hong Kong • Aim: Disease control
Last updated Mar 27, 2026 12:39 UTC
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Can the right exercise build stronger bones for women with diabetes?
Disease control CompletedThis study tested whether aerobic exercise or resistance training is better for improving bone density in postmenopausal women who have type 2 diabetes and are at risk for osteoporosis. Fifty women aged 50-60 participated in the completed trial. Researchers measured bone density …
Matched conditions: OSTEOPOROSIS
Phase: NA • Sponsor: Deraya University • Aim: Disease control
Last updated Mar 17, 2026 12:55 UTC
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VA launches major push to stop fractures in aging veterans
Disease control CompletedThis study tested a new, centralized 'Bone Health Service' model to improve how the VA healthcare system screens for and treats osteoporosis in older male veterans. It compared this new approach to usual care to see which was better at getting high-risk veterans screened, startin…
Matched conditions: OSTEOPOROSIS
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Disease control
Last updated Mar 16, 2026 15:24 UTC
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Simple hospital quiz aims to catch silent bone disease
Diagnosis CompletedThis study tested a new way to find osteoporosis in women aged 50-80 who were staying in the hospital. Researchers used a short questionnaire to check for risk factors. If risks were found, women were offered a bone density scan and referred to a specialist for treatment if neede…
Matched conditions: OSTEOPOROSIS
Sponsor: Centre Hospitalier Departemental Vendee • Aim: Diagnosis
Last updated Mar 23, 2026 15:17 UTC
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Can a fiber drink build stronger bones in teens?
Prevention CompletedThis study tested whether a daily drink containing soluble corn fiber, with or without added calcium, could help improve bone health in growing adolescents. Over 170 healthy teens aged 10-13 took part in this one-year trial, receiving either the fiber supplement, a placebo, or ve…
Matched conditions: OSTEOPOROSIS
Phase: PHASE2 • Sponsor: Florida International University • Aim: Prevention
Last updated Mar 25, 2026 14:08 UTC
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Video game therapy fights falls for breast cancer survivors
Symptom relief CompletedThis study tested whether playing balance games on a Wii Fit board could help women who have osteoporosis after a mastectomy. The goal was to see if this fun, at-home activity could improve their stability and lower their risk of falls. Researchers measured balance in 60 women be…
Matched conditions: OSTEOPOROSIS
Phase: NA • Sponsor: Cairo University • Aim: Symptom relief
Last updated Mar 30, 2026 14:28 UTC
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Scientists probe hidden link between stroke and weakening bones
Knowledge-focused CompletedThis study aimed to understand how a stroke affects bone strength, particularly in the hip. Researchers measured bone density in 44 stroke patients to see how it relates to factors like muscle strength, balance, and walking ability. The goal was to gather knowledge to help preven…
Matched conditions: OSTEOPOROSIS
Sponsor: Gaziler Physical Medicine and Rehabilitation Education and Research Hospital • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:12 UTC
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Can working nights weaken your bones? small study investigates
Knowledge-focused CompletedThis small research study aimed to understand if short-term night shift work disrupts the body's natural bone maintenance process. Researchers studied 20 healthy young adults to see if simulated night shifts temporarily altered blood markers related to bone building and breakdown…
Matched conditions: OSTEOPOROSIS
Phase: NA • Sponsor: University of Colorado, Denver • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:11 UTC
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Can AI teach you about bone health? new study investigates
Knowledge-focused CompletedThis study tested whether educational audio or video content created by an artificial intelligence (AI) program could help people learn more about osteoporosis. Researchers enrolled 60 adults aged 45 and older who either had osteoporosis or were at risk for it. Participants were …
Matched conditions: OSTEOPOROSIS
Phase: NA • Sponsor: Kars State Hospital • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:35 UTC
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New scan aims to predict broken bones in lung disease patients
Knowledge-focused CompletedThis study tested a new type of CT scan to see if it could better predict the risk of broken bones in people with Chronic Obstructive Pulmonary Disease (COPD). Researchers compared this new scan method to standard bone density tests in 560 current or former smokers, some with COP…
Matched conditions: OSTEOPOROSIS
Phase: NA • Sponsor: Punam K Saha • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:34 UTC
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Scientists track Anorexia's hidden toll on bones for six years
Knowledge-focused CompletedThis study aimed to understand why people with anorexia nervosa often lose bone density and develop osteoporosis. Researchers followed 180 patients with anorexia for up to 6 years, measuring their bone density every two years. They checked blood and urine for specific hormones fr…
Matched conditions: OSTEOPOROSIS
Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:29 UTC
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Can two scoops of yogurt a day strengthen aging bones?
Knowledge-focused CompletedThis study looked at whether eating Greek yogurt for 8 weeks could improve markers of bone health and reduce inflammation in adults over 55. Forty participants were assigned to eat yogurt, with or without exercise, or to continue their usual habits. Researchers measured blood mar…
Matched conditions: OSTEOPOROSIS
Phase: NA • Sponsor: Brock University • Aim: Knowledge-focused
Last updated Mar 25, 2026 14:08 UTC
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Scientists probe Fat-Bone connection in osteoporosis
Knowledge-focused CompletedThis study aimed to understand how secretions from fat cells might contribute to bone loss in osteoporosis. Researchers collected bone cells from 20 adults undergoing hip replacement surgery and exposed them to fat cell secretions in the lab. They measured how these secretions ch…
Matched conditions: OSTEOPOROSIS
Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Mar 19, 2026 14:55 UTC
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Could vitamin d levels predict metabolic health in seniors?
Knowledge-focused CompletedThis study looked at whether higher vitamin D levels are linked to a lower risk of metabolic syndrome (a cluster of conditions like high blood pressure and insulin resistance) in older adults who do not have a vitamin D deficiency. Researchers surveyed nearly 2,000 community-dwel…
Matched conditions: OSTEOPOROSIS
Sponsor: National Cheng-Kung University Hospital • Aim: Knowledge-focused
Last updated Mar 19, 2026 14:55 UTC
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Scientists test pill to replace bone disease shots
Knowledge-focused CompletedThis early study tested several new oral tablet formulations of a hormone (hPTH) used to treat bone diseases like osteoporosis. It involved 45 healthy male volunteers to see how the body absorbs these pills compared to an older oral tablet and a standard injection. The main goal …
Matched conditions: OSTEOPOROSIS
Phase: PHASE1 • Sponsor: Entera Bio Ltd. • Aim: Knowledge-focused
Last updated Mar 16, 2026 15:23 UTC
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Do HIV drugs cause other health problems? new study investigates
Knowledge-focused CompletedThis study aimed to understand if different types of HIV medications lead to different long-term health issues, like bone, kidney, or metabolic problems, in people living with HIV. Researchers followed 215 newly diagnosed, treatment-naive adults in Hong Kong for up to 5 years aft…
Matched conditions: OSTEOPOROSIS
Sponsor: Chinese University of Hong Kong • Aim: Knowledge-focused
Last updated Mar 09, 2026 14:24 UTC