OSTEOPOROSIS

This study looked at 54 people who need long-term steroids and have weak bones (osteoporosis). It compared two treatments: romosozumab followed by denosumab, versus denosumab alone, over 4 years. The goal was to see which approach better improves bone density and reduces fracture…

This study tested a 12-week program of exercise (resistance, aerobic, balance) plus a nutritional supplement (HMB) in 13 people with both osteoporosis and sarcopenia (muscle loss). Half received the program right away, while the other half waited. The goal was to see if the combi…

This study tested whether alendronate, a drug used for osteoporosis, can improve bone density in people with HIV. 140 participants received either alendronate or a placebo, along with calcium and vitamin D, for 2 years. The main goal was to measure changes in bone density in the …

This study looked at 44 postmenopausal women and men over 50 who had taken Denosumab for at least three years to treat osteoporosis. Researchers tested whether switching to Alendronate or Zoledronate could prevent bone density loss after stopping Denosumab. The goal was to find t…

This study tested a drug called denosumab in 24 adults with bone loss (osteoporosis) caused by systemic mastocytosis, a rare disease where certain immune cells build up. Participants received either denosumab or a placebo every 6 months for 3 years. The goal was to see if denosum…

This study tested whether eating Greek yogurt for 8 weeks could improve bone health and reduce inflammation in adults aged 55 and older. Some participants also took exercise classes. Researchers measured blood markers of bone turnover and inflammation to see if yogurt made a diff…

This pilot study tested whether a telehealth program combining strength training, balance exercises, and nutrition advice could help older men at high risk for falls and fractures. Forty-five men aged 60 and older participated. The goal was to see if the program was practical and…

This study looked at 45 adults with osteoporosis caused by long-term steroid use. Participants stopped taking denosumab and were switched to either zoledronic acid or alendronate at different times. The goal was to see which switch timing better controlled bone turnover and helpe…

This study tested whether a bone-building drug (teriparatide) and whole-body vibration, alone or together, can increase bone density in people with chronic spinal cord injury. 60 adults with low bone mass took part over 12 months. The goal was to see if these treatments could slo…

This study looked at whether taking soluble corn fiber (a type of dietary fiber) for one year could improve bone health in healthy adolescents aged 10-13. About 177 teens were randomly assigned to receive either the fiber supplement, fiber plus calcium, a placebo, or placebo plus…

This study tested a drug called romosozumab to see if it could improve bone health in women with chronic spinal cord injury and osteoporosis. Twelve women received monthly injections for one year, followed by a year of weekly alendronate pills. The goal was to measure changes in …

This study tested a simple questionnaire to find women at risk for osteoporosis, a bone-weakening disease that raises fracture risk. Over 3,200 women aged 50-80 who were hospitalized answered questions about risk factors, and those at risk were offered a bone density scan. The go…

This study looked at whether a single dose of zoledronic acid, a drug already used for osteoporosis, could prevent the rapid bone loss that often happens after a spinal cord injury. Researchers followed 60 adults who had recently been injured and could not walk independently. The…

This study looked at whether playing balance games on a Wii Fit board can help women with osteoporosis who have had a mastectomy improve their balance. Sixty women took part, and their balance was measured before and after eight weeks of playing the games. The goal was to see if …

This study looked at whether moderate aerobic exercise or resistance exercise is better for improving bone density in postmenopausal women with type 2 diabetes and osteoporosis. Fifty women aged 50 to 60 with a BMI of 30-35 took part. The goal was to see which type of exercise he…

This study tested whether a virtual rehabilitation program called VIVA is feasible for people with spine fractures caused by osteoporosis. The program includes weekly online sessions to help reduce pain and improve daily function. Researchers enrolled 34 participants across three…

This study tested a new way to predict bone fractures in people with osteoporosis. Standard bone density scans don't always tell who will break a bone. Researchers used a special CT scan to look at the inner structure of spine bones in 7 older women. The goal was to create a comp…

This study involved nearly 2,800 older adults to see if bone density and fracture information from routine CT scans could predict future spine fractures better than the standard FRAX risk score. Researchers used CT scans taken for other reasons to measure bone density and check f…

This study looked at 180 people with anorexia nervosa to understand why they lose bone density. Researchers measured bone mineral density and checked levels of fat-related hormones like leptin and adiponectin every two years for up to six years. The goal was to find connections b…

This study looked at 70 elderly women, some with osteoporosis and some without, to see if leg muscle strength is linked to bone density. Researchers measured hip and knee muscle strength and compared it to bone mineral density. The goal was to better understand risk factors for m…

This study looked at whether patient education classes for osteoporosis in Denmark improve quality of life, reduce fractures, and help with daily activities. Researchers compared over 3,100 people who took the classes with a similar group who did not. The goal was to see what wor…

This study followed 59 nurses during their first year of work to see if those working night shifts had worse bone health compared to day shift nurses. Researchers measured bone density and markers of bone turnover in the blood. The goal was to understand if chronic night shift wo…

This study followed 215 people newly diagnosed with HIV in Hong Kong to see how often they developed non-AIDS health problems like high blood pressure, diabetes, bone thinning, and kidney issues. Participants were on different anti-retroviral drug regimens, and researchers compar…

This study looked at 560 current or former smokers with and without COPD to see if a new CT-based method can better measure bone health and predict fracture risk. The goal was to create a tool that uses CT scans of the spine, hip, and ankle to assess bone structure, not just dens…

This study tested whether a few nights of simulated shift work can temporarily change how the body builds and breaks down bone. Twenty healthy adults aged 20-40 were monitored during two short hospital stays. The goal was to see if night work disrupts bone turnover and whether re…

This study looked at how fat cells in bone marrow may contribute to bone loss in osteoporosis. Researchers took bone samples from 20 adults undergoing hip replacement and tested how secretions from fat cells affected bone-forming cells in the lab. The goal was to better understan…

This early-stage study tested several new oral tablet versions of a bone-building hormone (hPTH(1-34)) in 45 healthy men aged 18-35. The goal was to see how well the body absorbs these new tablets compared to an existing oral tablet and a standard injection. The study focused on …

This study examined 549 older adults (65+) to see if metabolic syndrome is connected to vitamin D levels, even in those without vitamin D deficiency. Researchers used surveys and blood tests to gather data. The goal was to better understand these relationships, not to test a trea…

This study looked at different methods for screening male veterans for osteoporosis, a condition that weakens bones and raises fracture risk. Over 3,500 high-risk veterans took part, and researchers compared how well each screening approach worked. The goal was to find the most e…

This study tested whether short, AI-generated educational videos could help people aged 45 and older learn more about osteoporosis and improve their digital health skills. Sixty participants watched the videos and completed questionnaires before and after. The goal was to see if …

This study looked at how bone density changes over time in 82 postmenopausal women with rheumatoid arthritis. Researchers compared the effects of different arthritis medications and osteoporosis treatments on bone health. The goal was to understand which approaches might better p…

This study looked at how a natural cell cleanup process called autophagy affects bone health in older women with osteoporosis. Researchers compared bone samples from women with and without Alzheimer's disease to see if poor autophagy links the two conditions. The goal was to bett…

This study measured bone density in the hips of 44 stroke patients to see how the condition affects bone strength on the paralyzed and non-paralyzed sides. Researchers also checked muscle strength and other health factors. The goal was to better understand bone loss after a strok…