New CT tool could spot hidden fracture risk in COPD patients

NCT ID NCT03534934

Completed Knowledge-focused Sponsor: Punam K Saha Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether CT scans can better measure bone health and predict fracture risk in 560 smokers with and without COPD. Researchers used CT images of the spine and ankle to assess bone structure, alongside standard bone density tests. The goal is to create a more accurate tool for identifying osteoporosis risk in COPD patients.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could lead to a new CT-based tool that better predicts fracture risk in COPD patients, helping doctors prevent bone breaks.
What could go wrong: This is an observational study, not a treatment trial. The tool may not work as well in real-world settings or across different CT scanners.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

chronic obstructive pulmonary disease COPD, severe early onset osteoporosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OSTEOPOROSIS PULMONARY DISEASE, CHRONIC OBSTRUCTIVE

Contacts and locations

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Locations

Columbia University Medical Center

New York, New York, 10032, United States
University of Iowa Hospitals and Clinics

Iowa City, Iowa, 52242, United States

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