Bone drug shows promise for rare mast cell disorder

NCT ID NCT03401060

First seen Apr 11, 2026 · Last updated Jun 12, 2026 · Updated 11 times

Summary

This study tested whether denosumab, a drug given as a shot every 6 months, can improve bone density in people with osteoporosis caused by systemic mastocytosis. 24 adults with the condition took part. The goal was to see if the drug strengthens bones and prevents fractures better than a placebo.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for OSTEOPOROSIS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Locations

  • Caen Hospital, Clinical haematology department

    Caen, 14033, France

  • Cochin Hospital, Rheumatology department

    Paris, 75014, France

  • Estaing Hospital, Cellular therapy and clinical haematology department

    Clermont-Ferrand, 63100, France

  • Jean Minjoz Hospital, Dermatology department

    Besançon, 25030, France

  • La Pitié-Salpêtrière Hospital, Internal medicine and clinical immunology department

    Paris, 75013, France

  • La Timone Hospital, Dermatology and cutaneous oncology department

    Marseille, 13385, France

  • Lapeyronie Hospital, Rheumatology and Immunology department

    Montpellier, 34295, France

  • Lille CHRU Hospital, Internal medicine and clinical immunology department

    Lille, 59037, France

  • Necker Hospital, Adult haematology department

    Paris, 75015, France

  • Strasbourg Hospital, Rheumatology department

    Strasbourg, 67098, France

  • Toulouse Hospital, Dermatology department

    Toulouse, 31060, France

Conditions

Explore the condition pages connected to this study.