Study reveals bone risks from common skin treatment

NCT ID NCT03926377

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study looked at 47 people with bullous pemphigoid, a blistering skin condition, who were treated with high-dose topical corticosteroids (clobetasol propionate) for 6 months. Researchers measured bone mineral density at the start, at 3 months, and at 6 months to see if the treatment weakened bones. The goal was to understand the side effects of this standard therapy.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

clobetasol propionate (topical corticosteroid)

What this could lead to

If successful, this could help doctors understand the bone health risks of long-term topical steroid use in bullous pemphigoid patients.

What could go wrong

This is a small, completed Phase 4 study with only 47 participants, so results may not apply broadly. It measures bone density changes but does not test a new treatment.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

bullous pemphigoid osteoporosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHU Amiens

    Amiens, 80480, France