New hope for fragile bones: monthly shots may strengthen skeleton in paralyzed women

NCT ID NCT04708886

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This pilot study tested whether a year of monthly romosozumab injections, followed by a year of weekly alendronate pills, can improve bone health in women with chronic spinal cord injury and osteoporosis. Twelve non-ambulatory women participated. The goal was to see if this two-step approach increases bone density and reduces fracture risk.

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Conditions

The condition(s) this trial relates to.

Bone Diseases, Metabolic bone disorder osteoporosis spinal cord disorder spinal cord injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Northwestern University Feinberg School of Medicine

    Chicago, Illinois, 60611, United States