New hope for fragile bones: monthly shots may strengthen skeleton in paralyzed women

NCT ID NCT04708886

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This pilot study tested whether a year of monthly romosozumab injections, followed by a year of weekly alendronate pills, can improve bone health in women with chronic spinal cord injury and osteoporosis. Twelve non-ambulatory women participated. The goal was to see if this two-step approach increases bone density and reduces fracture risk.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Northwestern University Feinberg School of Medicine

    Chicago, Illinois, 60611, United States

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