BONE LOSS

This study looks at ways to prevent bone loss when older adults lose weight. It will test if a combination of resistance exercise and a bone-strengthening drug (alendronate) can protect bone density. About 900 overweight or obese older adults with low bone mass will take part for…

This study tests custom-made, 3D-printed hip implants for 15 adults whose previous hip replacements failed due to severe bone loss or infection. The implants are designed from CT scans to fit each person's unique bone damage. Researchers will track complications, pain, mobility, …

This study tests a new, less invasive surgical technique to rebuild bone in the upper jaw near the sinuses. The procedure uses a small window in the bone to lift the sinus membrane and add bone graft material, aiming to create enough bone for dental implants. The trial will enrol…

This study tests whether a monthly pill called risedronate can reduce bone and muscle loss after sleeve gastrectomy, a common weight-loss surgery. About 200 adults who have had the surgery will take either risedronate or a placebo for 6 months and be followed for a year. The goal…

This study looks at how well a full set of dental implants (All-on-X) works for people with bone loss in the upper jaw. Researchers will check implant survival and gum health over 2 years using special stackable guides for surgery. The goal is to see if this method helps patients…

This study tests whether adding a growth factor (rhPDGF) to a standard bone graft helps rebuild jawbone better than using saline alone. About 44 adults who need dental implants but have thin jawbone will receive one of the two treatments. Researchers will measure new bone formati…

This study tests whether taking a daily supplement of lutein, zeaxanthin, and fish oil for six months can improve thinking skills, eye health, and bone density in healthy adults. Researchers will enroll 80 people with low levels of a key eye pigment. Participants will take either…

This study looks at a new way to place dentures in the lower jaw using computer-guided surgery. The goal is to see if these implant-supported dentures help keep the jawbone healthy and last for at least 3 years. 40 adults aged 40-75 with no teeth in the lower jaw and enough bone …

This study uses two special scanners (HR-pQCT and pQCT) to take detailed pictures of bone and muscle in 1,000 people with conditions that raise the risk of bone loss, like osteoporosis, arthritis, or kidney disease. The goal is to see if these scanners can spot tiny changes in bo…

This study compares two different ways of placing dental implants to see which one leads to less bone loss after one year. Sixty adults with missing back teeth will be split into three groups, each receiving a slightly different implant procedure. Researchers will measure bone ch…