BONE LOSS

This study looks at how well a special type of denture, held in place by dental implants, works over 3 years. The implants are placed using a computer-guided method to be more precise. The goal is to see if this approach helps keep the jawbone healthy and the dentures stable. The…

This study looks for the best way to prevent bone loss when older adults lose weight. About 900 people with extra weight and low bone mass will try a combination of exercise, a bone-strengthening drug (alendronate), and a calorie-restricted diet. The goal is to keep bones strong …

This study tests if adding a special growth factor (rhPDGF) to donated bone particles helps rebuild jawbone better than using just salt water. About 44 adults who need dental implants but have thin jawbone will take part. Researchers will measure new bone growth after 4 months us…

This study looks at how well a full set of dental implants (All-on-X) works for people with bone loss in the upper jaw. Researchers used special stackable guides to place the implants and checked how many implants survived over 2 years. The goal is to see if this method is reliab…

This study tests a new, less invasive surgery to rebuild bone in the upper jaw for people who need dental implants. The procedure goes through the gum to lift the sinus membrane and add bone exactly where it's needed. About 20 adults with bone loss near the upper first molar will…

This study tests whether a monthly pill called risedronate can prevent bone and muscle loss that often happens after weight-loss surgery. About 200 adults who have had sleeve gastrectomy will take either risedronate or a placebo for 6 months and be followed for a year. Risedronat…

This study is testing custom-made, 3D-printed hip implants for 15 adults who have severe bone loss after failed hip replacement or infection. The implants are designed from CT scans to fit each person's unique bone damage. Researchers will track complications, pain, mobility, and…

This study looks at how different types of dental implant connections affect bone loss around the implant over one year. Sixty adults with missing back teeth will receive one of three implant attachment methods. The goal is to see which method keeps the bone around the implant mo…

This study uses two types of medical scanners to take detailed pictures of bone and muscle in 1,000 people with conditions like osteoporosis, arthritis, or kidney disease. The goal is to see how well these scanners measure bone structure and density, which may help doctors better…

This study looks at whether taking a daily supplement of lutein, zeaxanthin, and fish oil for six months can improve thinking skills, eye health, and bone density in healthy adults. Researchers will compare people who take the supplement to those who take a placebo. The goal is t…