BONE LOSS
Clinical trials for BONE LOSS explained in plain language.
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AI and donor teeth used to rebuild jaws for better implants
Disease control CompletedThis study tested two methods for rebuilding jawbone that has shrunk after tooth loss, to prepare it for dental implants. Researchers used processed, donated human tooth material (allogenic dentin) as a bone graft and artificial intelligence to create 3D models for surgical plann…
Matched conditions: BONE LOSS
Phase: NA • Sponsor: Kafrelsheikh University • Aim: Disease control
Last updated Apr 02, 2026 00:26 UTC
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Shake and inject: new combo fights bone loss in spinal injury patients
Disease control CompletedThis study tested whether a daily injection (teriparatide) and/or daily vibration therapy could help rebuild bone in people with long-term spinal cord injuries who cannot walk. Sixty participants were assigned to receive either the drug, the vibration, both, or neither for one ye…
Matched conditions: BONE LOSS
Phase: PHASE2 • Sponsor: Thomas J. Schnitzer • Aim: Disease control
Last updated Apr 01, 2026 14:43 UTC
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New hope for brittle bones in anorexia?
Disease control CompletedThis study tested whether a drug called denosumab could help improve bone strength in women with anorexia nervosa who have low bone density. Thirty participants were randomly assigned to receive either the drug or a placebo for one year. The goal was to see if the drug could incr…
Matched conditions: BONE LOSS
Phase: PHASE3 • Sponsor: Massachusetts General Hospital • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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Can a single infusion save bones after spinal injury?
Disease control CompletedThis study tested whether a medication called zoledronic acid could prevent the severe bone loss that often happens after a spinal cord injury. For two years, researchers compared the drug to a placebo in 60 adults who had a recent injury and could not walk independently. The goa…
Matched conditions: BONE LOSS
Phase: PHASE2 • Sponsor: Northwestern University • Aim: Disease control
Last updated Mar 30, 2026 14:32 UTC
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New hope for stronger bones after spinal injury
Disease control CompletedThis small, completed pilot study tested a two-step drug treatment to control bone loss in women with chronic spinal cord injury and osteoporosis. Twelve participants received monthly injections of romosozumab for one year to build bone, followed by a year of weekly alendronate p…
Matched conditions: BONE LOSS
Phase: PHASE2 • Sponsor: Northwestern University • Aim: Disease control
Last updated Mar 30, 2026 14:29 UTC
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Yogurt bacteria tested as a natural shield against brittle bones
Disease control CompletedThis study tested whether taking a specific probiotic (Lactobacillus acidophilus) could help control bone loss in women after menopause. Researchers gave the probiotic or a placebo to 90 women for several months to see if it improved their calcium levels and bone density. The goa…
Matched conditions: BONE LOSS
Phase: NA • Sponsor: Poznan University of Life Sciences • Aim: Disease control
Last updated Mar 24, 2026 12:02 UTC
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New hope for brittle bones in anorexia
Disease control CompletedThis study tested whether a drug called romosozumab could help improve bone density and strength in women with anorexia nervosa, a condition that often leads to weak, fragile bones. For 12 months, 30 participants received either the drug or a placebo (inactive substance) in a bli…
Matched conditions: BONE LOSS
Phase: PHASE3 • Sponsor: Karen Klahr Miller, MD • Aim: Disease control
Last updated Mar 20, 2026 14:48 UTC
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New CT technology aims to improve osteoporosis detection
Diagnosis CompletedThis study tested whether a new type of CT scanner can measure bone mineral density as well as the current standard DXA scan. Researchers compared bone density readings from both scans in 167 adults who needed a CT scan for medical reasons. The goal is to see if CT scans, which a…
Matched conditions: BONE LOSS
Phase: NA • Sponsor: Hatem Alkadhi • Aim: Diagnosis
Last updated Mar 24, 2026 12:02 UTC
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Can a simple shot save bones after weight loss surgery?
Prevention CompletedThis study tested whether a drug called denosumab could prevent bone loss that often happens after weight loss surgery. Researchers gave the drug or a placebo to 36 older adults who had either gastric bypass or sleeve gastrectomy surgery. The main goal was to see if the drug help…
Matched conditions: BONE LOSS
Phase: PHASE4 • Sponsor: Massachusetts General Hospital • Aim: Prevention
Last updated Mar 17, 2026 13:09 UTC