Can a daily injection and vibration rebuild bones after spinal cord injury?

NCT ID NCT01225055

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a bone-building drug (teriparatide) and a vibrating platform, alone or together, could improve bone density in 60 adults with chronic spinal cord injury who had low bone mass. Participants received daily injections of teriparatide, used a vibration device for 10 minutes a day, or both, for 12 months. The main goal was to see changes in hip bone density measured by DXA scans.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Teriparatide (Forteo) and whole-body vibration
What this could lead to
If successful, this combination could offer a way to strengthen bones and reduce fracture risk in people with chronic spinal cord injury.
What could go wrong
This is a small, early-phase trial with only 60 participants. Results may not apply to everyone, and the treatment requires daily injections and a device, which may be burdensome.

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Conditions

The condition(s) this trial relates to.

Bone Diseases, Metabolic osteoporosis spinal cord injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Edward Hines, Jr, VA Hospital

    Maywood, Illinois, 60153, United States

  • Northwestern University Feinberg School of Medicine

    Chicago, Illinois, 60611, United States

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