OBSTRUCTIVE SLEEP APNEA

This study is investigating whether treating sleep apnea with CPAP therapy can improve metabolic and hormonal health in women with Polycystic Ovary Syndrome (PCOS). Researchers are enrolling 20 women with both PCOS and moderate-to-severe sleep apnea to test if using a CPAP machin…

This study aims to see if showing sleep apnea patients how their CPAP machine usage compares to other patients helps them use the machine more consistently. About 186 adults already using CPAP therapy will be randomly assigned to receive either just their own usage data or that d…

This study looks back at data from 10,000 people with obstructive sleep apnea to see if a common treatment (CPAP therapy) lowers blood pressure differently depending on whether the patient feels very sleepy during the day. Researchers want to know if sleepy patients get a bigger …

This study aims to find out if removing certain upper teeth (premolars) during braces treatment makes sleep apnea worse in children with prominent front teeth. Researchers will compare sleep study results from children who have teeth removed to those who don't. The goal is to see…

This study is testing whether annual follow-up visits for sleep apnea patients using CPAP machines can be done effectively by video call (tele-visit) instead of an in-person home visit. It involves 320 adults who have been using their CPAP machine for at least a year. The main go…

This study is testing if a surgically implanted device that treats sleep apnea can also improve thinking skills and language in adolescents and young adults with Down syndrome. The device stimulates a nerve to keep the airway open during sleep. Researchers will follow 57 particip…

This study is following children with weak muscles (hypotonia) who have trouble breathing during sleep due to a blocked airway. Researchers are checking if a small, flexible tube placed in the nose helps keep the airway open over the long term, improves sleep quality, and is comf…

This study is tracking 110 adults with moderate to severe obstructive sleep apnea (OSA) for five years after they receive the Genio system, a small implanted device. The goal is to confirm the long-term safety of the device and see how well it continues to reduce breathing pauses…

This small Mayo Clinic study is testing whether a nightly automated neck massage device can help improve the brain's natural waste-clearing system in people with treated sleep apnea. Researchers will measure changes in blood markers linked to brain health and sleep quality after …

This study aimed to see if treating sleep apnea with a CPAP machine could improve insulin resistance and heart function in people who also have heart failure. It planned to measure changes in blood sugar control, certain blood proteins, and heart health using MRI scans. The trial…

This study is testing whether using a special breathing machine at night for six months can improve how the heart uses energy and how its nerves function in people who have both heart failure and sleep apnea. Researchers will use advanced heart scans to measure changes in 60 part…

This study is testing if a common sleep medication called trazodone can slow down memory loss in people who have both early-stage memory problems (mild cognitive impairment) and obstructive sleep apnea. Researchers believe treating sleep apnea might help protect the brain. Over o…

This study is testing whether a simple, 5-minute daily breathing exercise can help lower high blood pressure and improve heart health in adults aged 50 and older who have moderate to severe obstructive sleep apnea. Researchers are comparing a high-intensity breathing training pro…

This large, long-term study is analyzing health records to see if effectively treating both obstructive sleep apnea and high blood pressure can prevent serious heart problems or death. It will follow 10,000 patients to compare outcomes between those who use their sleep apnea mach…

This study is testing a new computer modeling tool to help doctors predict whether surgery will successfully treat obstructive sleep apnea in children and young adults with Down Syndrome. Researchers will use MRI scans taken during sleep to create personalized computer models of …

This study is testing how accurate a new, comfortable mouthpiece device is at measuring drops in oxygen levels during sleep in people with obstructive sleep apnea. The device is worn like a dental retainer and will be compared against the standard, more complex sleep lab test. Th…

This study is testing whether short video clips recorded by parents on their smartphones can help screen children with Down syndrome for obstructive sleep apnea (OSA). Parents and doctors will watch the videos and guess if the child has OSA, and then compare those guesses to resu…

This study is testing if a drink containing ketones (Ketone-IQ) taken before bed can improve sleep and breathing for people with obstructive sleep apnea (OSA). Researchers want to see if this supplement is a practical alternative to a strict ketogenic diet, which has shown benefi…

This study aims to understand how stimulating specific throat muscles affects airway collapse in people with obstructive sleep apnea. Researchers will test a muscle stimulator on 60 adults during a standard sleep endoscopy procedure. The goal is to gather basic measurements about…

This study aims to understand how common obstructive sleep apnea is in adult survivors of Hodgkin lymphoma who were treated with chest radiation. Researchers will compare 220 survivors to a group of healthy people matched for age, gender, race, and weight. The study involves slee…

This study aimed to learn more about a specific nerve in the throat (the glossopharyngeal nerve) and see if electrically stimulating it during surgery could help keep the airway open. It planned to involve adults with sleep apnea who were already scheduled for surgery to remove a…

This study aims to check if standard sleep questionnaires work well for children with Down syndrome. Researchers are enrolling 81 children with Down syndrome, aged 2-17, to see if these paper surveys can accurately screen for obstructive sleep apnea. The goal is to find easier, c…

This small study is testing whether a supplement called N-acetylcysteine (NAC) affects the body's stress and inflammation levels differently in men and women with obstructive sleep apnea. Participants already using standard sleep apnea therapy will take either NAC or a placebo fo…

This study aimed to understand how obstructive sleep apnea (OSA) worsens the natural decline in testosterone levels as men age. Researchers planned to compare hormone levels in men with untreated OSA to those using CPAP therapy. The goal was to identify the specific biological me…

This study looks back at medical records to see if keeping the breathing tube in place longer after stomach cancer surgery (24-48 hours instead of removing it sooner) affects complication rates. It focuses on patients who also have severe obstructive sleep apnea, a condition that…

This study aims to understand if sleep-disordered breathing (like snoring or sleep apnea) affects how scoliosis curves progress in children. Researchers are observing 405 children with mild to moderate scoliosis over several years, checking their sleep patterns and measuring thei…