New implant aims to control sleep apnea without a mask

NCT ID NCT04031040

First seen Jan 07, 2026 · Last updated May 02, 2026 · Updated 19 times

Summary

This study follows 110 adults with moderate to severe obstructive sleep apnea who have not tolerated or refused standard treatments like CPAP. The Genio® system is an implanted device that stimulates the airway during sleep to keep it open. Researchers will track safety and effectiveness over 5 years, measuring breathing pauses and quality of life.

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Contacts and locations

Locations

  • Asklepios Klinikum Harburg, Abt. für HNO-Heilkunde, Kopf- und Halschirurgie

    Hamburg, 21075, Germany

  • CEREVES Paris Jean Jaurès - Centre du sommeil

    Paris, 75019, France

  • CHU - Angers

    Angers, 49933, France

  • CHU Toulouse

    Toulouse, 31400, France

  • Clinique Beau-Soleil

    Montpellier, 34070, France

  • Clinique Mutualiste de la Sagesse

    Rennes, 35000, France

  • HNO-Klinik des Universitätsklinikums Jena

    Jena, 07747, Germany

  • Helios Universitätsklinikum Wuppertal,Klinik für Hals-Nasen-Ohrenheilkunde, Kopf- und Halschirurgie

    Wuppertal, 42283, Germany

  • Hôpital Bichat, Assistance Publique - Hôpitaux de Paris

    Paris, 75018, France

  • Hôpital Henri-Mondor AP-HP

    Créteil, 94010, France

  • Hôpital Privé La Louvière

    Lille, 59800, France

  • Hôpital Tenon AP-HP

    Paris, 75020, France

  • Kantonsspital Baselland, Klinik für HNO-Krankheiten, Kopf- und Gesichtschirurgie

    Liestal, 4410, Switzerland

  • Klinik für HNO-Heilkunde, Kopf- und Halschirurgie, Schlafmedizinisches Zentrum

    Mannheim, 68167, Germany

  • Klinikum rechts der Isar der TU München

    München, 81675, Germany

  • Onze Lieve Vrouwe Gasthuis

    Amsterdam, 1061 AE, Netherlands

  • Polyclinique Saint Laurent

    Rennes, 35700, France

  • Universitair Ziekenhuis Antwerpen

    Antwerp, 2650, Belgium

  • Ziekenhuis Netwerk Antwerpen - ZNA Jan Palfijn

    Antwerp, 2170, Belgium

Conditions

Explore the condition pages connected to this study.