Could a simple questionnaire spot sleep apnea in kids with down syndrome?

NCT ID NCT03771469

Ongoing Knowledge-focused Sponsor: Oregon Health and Science University Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 2 times

Summary

This study checks whether sleep questionnaires can reliably detect obstructive sleep apnea (OSA) in children with Down syndrome, who are at higher risk for the condition. Researchers will compare questionnaire results with overnight sleep studies (the gold standard) in about 81 children aged 2-17. If the questionnaires prove accurate, they could offer a simpler, less burdensome way to screen for OSA in this population.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could provide a simple questionnaire to screen for sleep apnea in children with Down syndrome, reducing the need for overnight sleep studies.
What could go wrong: This is an observational validation study, not a treatment trial. The questionnaires may not be accurate enough to replace sleep studies, and results may not apply to all children with Down syndrome.

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Conditions

The condition(s) this trial relates to.

Down syndrome obstructive sleep apnea syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DOWN SYNDROME OBSTRUCTIVE SLEEP APNEA

Contacts and locations

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Locations

Doernbecher Children's Hospital

Portland, Oregon, 97239, United States

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