Sleep Apnea-Diabetes link under microscope in new study

NCT ID NCT04234217

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how sleep apnea might cause prediabetes to turn into diabetes. Researchers will use CPAP machines and niacin infusions in 300 overweight, prediabetic adults with sleep apnea to measure changes in blood chemicals. The goal is to understand the biological steps involved, not to test a new treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Continuous positive airway pressure (CPAP) device and niacin infusion

What this could lead to

If successful, this could reveal how sleep apnea contributes to diabetes, pointing toward new prevention strategies.

What could go wrong

This is an observational/mechanistic study, not a treatment trial. It may not lead directly to new therapies, and results may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

glucose intolerance obstructive sleep apnea syndrome prediabetes syndrome sleep apnea syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Chicago

    Chicago, Illinois, 60637, United States