PRE DIABETES

This study tests whether personalized marketing and discounts in an online grocery store can encourage people with prediabetes or type 2 diabetes to buy more whole grains instead of refined grains. About 216 adults aged 45-70 from Pennsylvania who already shop online for grocerie…

This study tests whether two approved drugs, mirabegron and tadalafil, can improve how the body handles sugar in people with prediabetes and obesity. About 96 adults will take one or both drugs or a placebo for 14 weeks. The goal is to see if these drugs can reverse prediabetes a…

This study looks at whether having a stable daily routine—like consistent meal times and sleep—can improve blood sugar control and reduce body fat in people with pre-diabetes. About 34 adults with pre-diabetes and a BMI between 25 and 40 will be tracked. The goal is to see if thi…

This study tests whether a program led by community health workers can help migrant farmworker women ages 18-45 reduce stress, feel less isolated, and improve heart health. Participants will either receive peer support and help finding community resources, or just basic health in…

This study compares two healthy diets—one centered on lean beef and one following a standard US pattern—to see which better lowers inflammation in adults with metabolic syndrome or pre-diabetes. Over 5 weeks, researchers will measure changes in blood markers of inflammation and o…

This study looks at whether time-restricted eating (eating all meals within a set daily window) can improve health markers like blood sugar and cholesterol in people with metabolic syndrome or pre-diabetes. About 140 adults who typically eat over 12 hours a day will be randomly a…

This study compares a self-administered oral glucose tolerance test (OGTT) at home using a continuous glucose monitor (CGM) with the standard clinic-based OGTT. 75 adults with prediabetes will do both tests to see if the home version is accurate and practical. The goal is to make…

This study looks at whether drinking one cup of regular milk each day can lower the risk of type 2 diabetes in people with lactose intolerance who also have prediabetes. Researchers will compare regular milk to lactose-free milk over 12 weeks in 40 adults. They will measure chang…

This study looks at whether using a sit-stand desk at work can help prevent type 2 diabetes in people who are overweight and sit most of the day. About 198 adults with prediabetes or other risk factors will be randomly assigned to stand 2 or 3 hours daily at their desk, or to a c…

This study tests new, low-cost treatments to help Hispanic adults with prediabetes and obesity. The goal is to bring blood sugar back to normal, help with weight loss, and lower the risk of heart problems. Researchers will check how these treatments affect metabolism and body fun…

This study tests whether adding reminders to electronic medical records helps doctors provide better care for people with pre-diabetes. About 6000 adults aged 21-59 will take part. Some clinics will use the reminders; others will not. The goal is to see if the prompts lead to mor…

This study aims to identify people at increased risk of developing type 1 diabetes by testing for specific markers in the blood called autoantibodies. Researchers are recruiting 30,000 children and adults aged 1 to 45 who have a family member or close friend diagnosed with type 1…

This study aims to understand how blood sugar levels vary throughout the day in people with and without prediabetes. Researchers will use a continuous glucose monitor (FreeStyle Libre 3) to collect data from 2,000 adults. The goal is to identify patterns that could help improve e…

This study looks at why people with pre-diabetes or type 2 diabetes feel more tired and weak in their legs during exercise. Researchers think it may be due to blood vessel problems. They will test a special exercise program that uses blood flow restriction to better understand th…

This study tests whether wearing a continuous glucose monitor (CGM) helps adults with prediabetes improve their diet and activity levels compared to standard health coaching. About 76 participants will be randomly assigned to receive either a CGM plus coaching or coaching alone. …