OBESITY; OVERWEIGHT

This study tested whether personalized diet advice based on a person's gut bacteria could improve their food choices and gut health. Fifty adults with obesity in Colombia were split into two groups: one got standard diet advice, the other got a custom plan based on their gut micr…

This study looked at how well adults with obesity or complicated overweight can stick with different very-low-calorie ketogenic diets. Participants chose one of four diet types, ranging from natural foods to meal replacements, and followed a 26-week program. The goal was to see w…

This study looked at whether intermittent fasting or a Mediterranean diet helps overweight and obese adults lose body fat and improve their eating habits. One hundred people took part, and researchers measured changes in body composition and nutrition knowledge. The goal was to f…

This study tested whether special food supplement capsules that release nutrients in the lower gut can increase appetite-regulating hormones and reduce food intake. Twenty adults with obesity took either the active supplement or a placebo on separate days, and researchers measure…

This study looked at how tirzepatide, a medication already used for weight loss, works in real-world settings for two groups: people who regained weight after bariatric surgery and people with obesity preparing for surgery. Researchers tracked weight and metabolic changes over 6 …

This study looked at how a very low-calorie ketogenic diet (VLCKD) affects body weight and energy use in people with obesity. Seventeen participants followed the diet and were monitored for changes in body composition and metabolism. The goal was to understand long-term effects o…

This study looked at whether adding a protein supplement to a small meal on fasting days could help young men with overweight lose body fat while keeping their muscle. Twenty-six men aged 21-35 followed a 4-week alternate-day fasting plan. Some received a protein drink on fasting…

This study tested whether gummy candies made with maqui berry could help control blood sugar and increase antioxidant levels in overweight adults. Ten participants ate a carbohydrate-rich food with or without the gummies on three separate visits. Researchers measured blood sugar …

This study tested a web-based tool called WeDosify that helps doctors manage semaglutide dosing for adults with overweight or obesity. Twenty participants who had recently started semaglutide used the tool over three months. The main goal was to see how many stayed on the treatme…

This study looked at whether laparoscopic sleeve gastrectomy (a weight-loss surgery) helps adults over 65 with severe obesity and related conditions like type 2 diabetes, high blood pressure, sleep apnea, and knee arthritis. Sixty participants chose either surgery or standard car…

This study tested the SWW Method®, a 12-week diet and lifestyle program, in 85 women aged 35-75. The program included intermittent fasting, a protein-rich diet, and other healthy habits. Researchers measured changes in blood sugar, weight, and other metabolic markers compared to …

This study looked at how well a smartphone app that uses breath biofeedback helps people with overweight or obesity lose weight over two years. Over 11,500 adults used the app as part of their normal routine, and researchers analyzed their weight data. The goal was to see how muc…

This study looked at whether adding mindful eating training to a weight-loss diet helps adults with obesity eat more mindfully and feel less driven by food cravings. 82 adults with obesity took part. Researchers compared those who only followed a weight-loss diet to those who als…

This study looked at whether standing on a vibrating platform while doing foot exercises could improve ankle strength, balance, and body awareness in overweight and obese young adults (ages 18-35). Twenty-six people completed 24 supervised sessions over 8 weeks. The results help …

This study tested a daily injection called ROSE-010 in 40 overweight and obese women to see if it reduces appetite and food intake. Participants received either the drug or a placebo, and researchers measured how much they ate at lunch and their hunger levels. The goal was to fin…

This study looked at whether adding TECAR therapy or shock wave therapy to standard lymphedema care helps reduce leg swelling in severely obese women. Forty-five women received either standard care alone or combined with one of the two extra treatments over four weeks. Researcher…

This study tested a new 'hook technique' for giving breaths to obese patients (BMI 30-40) during medical procedures. It compared the hook method to two standard one-hand ventilation techniques. The goal was to see which method works best and fastest to get enough air into the lun…

This study followed 22 adults with obesity who underwent a standard diet and lifestyle program to lose weight. Researchers measured changes in body weight, fat distribution, and metabolism over 12 months. The goal was to better understand how the body adapts during weight loss, n…

This study looked at 150 adults with normal weight, overweight, or obesity to see if a nutrition plan based on both genes and body measurements works better than one based only on body measurements. Participants followed a six-month diet plan, and researchers tracked changes in w…

This study tested whether two different doses of dietary supplements (DIM and Perilla oil) delivered to the lower gut could reduce appetite and food intake in 16 adults with obesity. Participants fasted, took capsules, and had blood drawn every 30 minutes to measure hunger hormon…

This study looked at 22 overweight adults with headaches to see if walking exercise and changes in body fat affect brain structure. Participants either followed a diet plus a 12-week walking program or diet alone. Brain scans and body measurements were taken before and after to t…

This study looked at 40 adults with severe obesity who had laparoscopic sleeve gastrectomy, a common weight-loss surgery. Researchers measured blood levels of isthmin, a protein involved in metabolism, before and after surgery. The goal was to see if isthmin levels change after t…

This study looked at how sleep quality, when people eat, and gut bacteria are connected to obesity. It included 133 adults with different body weights and sleep issues. The goal was to understand these links and test a simple e-health tool to help people make healthier lifestyle …

This study tested a single dose of VCT220 in 16 people to see how kidney function affects the drug. Half had moderate kidney problems, half had normal kidneys. The goal was to learn how to dose the drug safely for people with kidney issues.

This study tested a single injection of petrelintide at different concentrations in 48 adults with a BMI of 27 or higher. The goal was to see how the body processes the drug and whether different concentrations affect safety. Participants were monitored for about 50 days. This wa…

This study used health records from over 450,000 adults with obesity and type 2 diabetes to see if adding a second medication early (like GLP-1 or SGLT2 drugs) improves survival and kidney health. Researchers compared those who added another drug within 90 days to those who did n…

This study looked at over 200,000 adults with obesity and type 2 diabetes to see if the type of diabetes medication they took before a cancer diagnosis affected their survival and health after cancer. Researchers compared GLP-1 receptor agonists (like Ozempic) with other diabetes…

This study examined whether a simple CT scan before weight-loss surgery can help predict when a surgeon might need to change their planned approach during the operation. Researchers looked back at records of 288 adults who had gastric bypass surgery at a French hospital over 10 y…

This study tested whether giving two weight-loss medications (cagrilintide and semaglutide) as a single combined injection works the same as giving them separately. Forty adults with overweight or obesity received weekly injections for 22 weeks. The goal was to measure medicine l…

This early-stage study tested whether a new probiotic bacterium, Phascolarctobacterium faecium, is safe and well-tolerated in people. Twenty healthy adults with normal weight or overweight took the bacterium daily for 15 days. Researchers monitored for side effects, changes in bl…

This study examined 821 first-year university students in Spain to understand how their physical activity and sitting habits relate to obesity and muscle/joint health. Researchers used a questionnaire to measure activity levels and body mass index (BMI) to classify weight. The go…

This study looked at how losing at least 10% of body weight changes the heart's shape and function in people who are overweight or obese and have heart risk factors. Researchers used heart scans and blood tests to measure these changes. The goal was to understand if weight loss c…