OBESITY & OVERWEIGHT

This study tested a web-based tool called WeDosify, designed to help doctors personalize dosing for the weight-loss medication semaglutide (like Wegovy). It involved 20 adults with overweight or obesity who were already starting this medication. The main goal was to see if using …

This study looked at how the weight-loss medication tirzepatide works for people in two real-world situations: those who have regained a significant amount of weight after bariatric surgery, and those who need to lose weight before having obesity surgery. Researchers followed 254…

This study tested whether personalized diet recommendations, created by analyzing a person's gut bacteria, could improve health in adults with obesity. Fifty participants in Colombia were randomly assigned to follow a 12-week personalized diet plan or continue their usual habits.…

This study tested a new drug called ROSE-010 to see if it could help control weight by reducing appetite and food intake. It involved 40 overweight or obese women who received either the drug or a placebo for one week. Researchers measured how much food participants ate at lunch …

This small, completed study aimed to understand the long-term effects of a very low-calorie ketogenic diet (VLCKD) on people with obesity. It followed 17 participants for 6 to 12 months to see how the diet changed their body weight, body composition, and daily energy use. The mai…

This study aimed to see which of two popular dietary approaches—intermittent fasting or the Mediterranean diet—was more effective for improving body composition and nutrition in overweight and obese adults. One hundred participants were randomly assigned to follow one of these ea…

This study tested if adding a protein supplement to an alternate-day fasting diet helps young men with overweight or obesity. For four weeks, participants fasted every other day, eating only one small meal. Researchers checked if the protein helped them lose more fat while preser…

This small, completed study tested whether gummy candies made from maqui berry could help control blood sugar and antioxidant levels in overweight adults. Ten participants ate white bread alone, bread with regular gummies, and bread with a special encapsulated gummy version on se…

This study looked at whether losing at least 10% of body weight could improve the structure and function of the heart in people who are overweight or obese and have heart disease risk factors. Researchers followed 30 adults, using heart scans and blood tests to measure changes af…

This study tested whether giving two weight management medications together in one injection works as well as giving them as two separate injections. It involved 40 adults with overweight or obesity who received weekly injections for 22 weeks. Researchers measured how the body pr…

This study followed 110 adults with obesity or overweight plus liver disease to see how well they could stick to different versions of a very-low-calorie ketogenic diet in regular medical care. Participants chose from four diet plans that varied in how much they used natural food…

This study compared weight loss surgery to standard medical care in 60 adults aged 65 and older who had severe obesity and related health issues like type 2 diabetes, high blood pressure, sleep apnea, or knee arthritis. Over 12 months, researchers tracked which treatment led to b…

This study looked back at data from over 11,500 adults who were overweight or obese and used a specific mobile app. The app uses breath biofeedback to help with weight management. Researchers analyzed the users' weight data over two years to see how much weight they lost and if t…

This large study looked back at health records of over 450,000 adults with type 2 diabetes and obesity to see if starting two newer types of diabetes drugs (GLP-1s and SGLT2is) close together is better than other strategies. It aimed to find out which early drug combination leads…

This study tested a 12-week diet and lifestyle program called the SWW Method to see if it could help women improve their blood sugar levels and manage their weight. The program included guidance on fasting, meal timing, and protein-focused eating. Researchers compared 45 women wh…

This study tested whether adding mindful eating training to a standard weight-loss diet helps people with obesity better control their food cravings and lose weight. Researchers compared 82 adults on a diet alone to those who also received mindful eating lessons. They measured ch…

This study tested whether special food supplement capsules, designed to release their contents in the lower gut, could help people with obesity feel fuller and eat less. Twenty adults with obesity took either the active supplement or a placebo during two separate visits. Research…

This study observed 22 adults with obesity who followed a supervised diet and lifestyle program for one year. Researchers tracked their weight loss and took small fat tissue samples to see how their metabolism and body fat changed. The goal was to better understand why people res…

This study aimed to understand how a specific body chemical, isthmin, changes after a common weight-loss surgery. Researchers measured isthmin levels in 40 adults with severe obesity before and after they underwent laparoscopic sleeve gastrectomy. The goal was to gather knowledge…

This early-stage study aimed to see if a new type of probiotic bacterium is safe and easy to take. Twenty adults, including some with overweight or blood sugar concerns, took the probiotic daily for 15 days. Researchers checked for side effects and changes in blood tests and gut …

This early study tested how a single dose of an experimental obesity medication called VCT220 is processed by the body in people with moderate kidney problems compared to people with normal kidney function. Sixteen participants received the drug and had their blood monitored for …

This study aimed to understand the connections between sleep quality, when people eat during the day, gut bacteria, and body weight. Researchers enrolled 133 adults with different body weights and sleep patterns to gather this information. They also developed and tested a simple …

This study aimed to see if a nutrition plan tailored to a person's genes and body measurements works better than a standard plan based only on body measurements. It involved 150 adults of different weights who followed one of these two diet plans for six months. Researchers measu…

This study aimed to understand if a 12-week walking and diet program could change brain structure in overweight adults who also have headaches. Researchers compared 22 participants split into two groups: one did diet and walking, the other diet alone. They used brain scans and bo…

This completed study looked at the activity levels and sitting habits of over 800 first-year university students in Spain. Researchers used questionnaires to understand how these behaviors relate to students' weight and potential muscle and bone health risks. The goal was to gath…

This study looked back at past patients to see if a simple CT scan before weight-loss surgery could help predict when surgeons might need to change their plan during the operation. Researchers compared 288 patients who had their planned surgery changed to those who did not, check…