Weight-Loss drug shows promise for regain after gastric sleeve

NCT ID NCT07382180

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This completed study looked at how tirzepatide, a weight-loss drug, works in real-world settings for two groups: people who regained weight after gastric sleeve surgery, and those preparing for obesity surgery. Researchers tracked weight and metabolic changes over 6 months in 254 adults. The goal was to see if tirzepatide helps manage weight in these challenging situations.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
tirzepatide
What this could lead to
If results are positive, this could support using tirzepatide as a standard option for managing weight regain after bariatric surgery or before surgery.
What could go wrong
This is an observational study, not a controlled trial, so results may be influenced by patient selection and other factors. It does not prove long-term safety or effectiveness.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Head of bariatric surgery

    Naples, 80131, Italy

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Other studies related to the condition(s) this trial covers.