Can a very low calorie diet keep weight off long term? small study investigates
NCT ID NCT07418281
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study from the University of Pisa examined how a very low calorie ketogenic diet (VLCKD) affects body weight and energy use over time in 17 people with obesity. Participants followed the diet and were then monitored for changes in body composition and 24-hour metabolism. The goal was to see if the diet leads to lasting weight loss and metabolic improvements.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- very low calorie ketogenic diet (VLCKD)
- What this could lead to
- If successful, this could help clarify whether VLCKD leads to lasting weight loss and metabolic changes in people with obesity.
- What could go wrong
- This is a small, completed study with only 17 participants and no control group, so results may not apply broadly. Long-term safety and effectiveness are not established.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Univeristy Hospital of Pisa
Pisa, 56124, Italy
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