LUMBAR DISC HERNIATION

This study tests whether applying a steroid (dexamethasone) directly to the surgical site during herniated disc surgery can lower pain and disability afterward. About 200 adults with a single-level lumbar disc herniation who have not improved with rest or therapy will be randomly…

This study tests whether ice cubes, mouthwash, or menthol lozenges can help reduce nausea and thirst and improve comfort in 128 adults after spine surgery. Participants will be randomly assigned to one of the three methods, and their symptoms will be measured using simple scales.…

This study tests a device called Discogen that uses low-intensity ultrasound to treat pain from a herniated disc. About 40 adults with leg or back pain will receive either the real treatment or a sham (fake) treatment. The goal is to see if the device safely reduces pain and impr…

This study tests whether two hands-on therapies—instrument-assisted soft tissue mobilization and vibration massage—can reduce pain, improve daily function, and lessen fear of movement in people with lumbar disc herniation (a slipped disc). Researchers will enroll 45 adults aged 3…

This study compares two types of ultrasound-guided nerve blocks given before lumbar microdiscectomy (a type of back surgery) to see which one provides better pain relief. Eighty adults aged 18-65 will be randomly assigned to receive one of the two blocks. The main goal is to meas…

This study looks at whether avoiding opioids during back surgery can still control pain and reduce side effects like nausea and constipation. About 75 adults having elective lumbar spine surgery will be placed into one of three groups based on their anesthesia plan. The goal is t…

This study tests whether a nerve block called an erector spinae plane block can help control pain and reduce the need for opioid painkillers after minimally invasive lumbar spine surgery. About 125 adults having specific types of back surgery will receive either the nerve block o…

This study tests whether adding a laser pointer to standard stabilization exercises helps people recover better after lumbar microdiscectomy surgery. 42 adults aged 18-65 will be split into two groups: one doing standard exercises and one doing the same exercises with a laser poi…

This study tests whether a type of physical therapy called TECAR (focused radiofrequency) can reduce pain and improve daily function in people with lumbar disc herniation (a slipped disc). Researchers will enroll 54 adults aged 20-60 who have had low back pain for more than 12 we…

This study compares two types of nerve blocks (TLIP and Quadro Iliac) to see which one better reduces pain and the need for strong painkillers after lumbar microdiscectomy surgery for herniated discs. About 90 adults having this back surgery will receive one of the two blocks bef…

This study tests whether taking a special probiotic (OMNi-BiOTiC® Hetox) can improve healing, reduce pain, and lower complications after neurosurgery for back or neck problems. About 110 adults having spine surgery will be randomly assigned to receive either the probiotic or a pl…

This study looks at whether listening to ney music, a traditional Turkish wind instrument, can help people who have had lumbar disc surgery feel less pain and anxiety, sleep better, and have a better quality of life. About 60 adults will be split into two groups: one group will l…

This study tests a gentle exercise program combining Baduanjin (a traditional Chinese mind-body practice) with resistance training for older adults with osteoporosis and a slipped disc in the lower back. Researchers want to see if it can reduce pain, improve muscle strength, and …

This study compares two common treatments for back and leg pain caused by a herniated disc: a lumbar erector spinae plane block (an injection near the spine muscles) and a lumbar epidural steroid injection (an injection into the spine's outer layer). Researchers will track pain l…

This study looks at whether giving a nerve block (ESPB) before or during lumbar disc surgery better reduces pain and the need for strong painkillers. Sixty adults having back surgery will be split into two groups: one gets the block before surgery, the other during. The goal is t…

This study compares non-drug treatments (acupuncture, spinal manipulation) with standard medications (painkillers, injections) for people with a herniated disc in the lower back who have had pain for at least a month. 200 adults aged 19-69 will be randomly assigned to one of the …

This study is testing whether starting rehabilitation exercises earlier or later after back surgery for a herniated disc leads to better pain and function. Seventy-two adults aged 19 to 65 will follow a standardized exercise program guided by a physical therapist. The main goal i…

This study looks at how fear-avoidance beliefs—the fear that moving will cause more pain or injury—relate to trunk muscle endurance, balance, and daily function in people with lumbar disc herniation (a slipped disc). Researchers will measure these factors in 65 adults aged 18 to …

This study will check if a protein called periostin in the blood is related to how much back pain limits daily activities and quality of life. Researchers will measure periostin in 38 adults with lumbar disc problems and compare it to their scores on disability and health questio…

This study looks at whether taking NSAIDs (like ibuprofen) changes the level of a protein called periostin in the blood of people with degenerative disc disease. Researchers will compare three groups: patients using NSAIDs, patients not using NSAIDs, and healthy people without ba…

This study compares two ways of using a breathing machine during surgery for a slipped disk in the lower back. One method controls the flow of air, the other controls the volume. Researchers want to see which keeps oxygen levels higher after patients are turned onto their stomach…

This study is looking at why some people recover leg strength better than others after surgery for a slipped disc. Researchers will follow 40 patients who have leg weakness before surgery and track factors like age, weight, and how long they had weakness. The goal is to find out …