LUMBAR DISC HERNIATION

This early-stage trial tests whether injecting stem cells from donated umbilical cords into the spine can help repair degenerated discs in people with lower back and leg pain. Twenty patients who have not improved with other treatments will receive the injection right after a min…

This study tests a new gel, MegaShield-SP, to see if it prevents scar tissue after spine surgery better than an existing gel. About 80 adults aged 20-70 with a herniated disc or spinal stenosis will receive one of the two gels during surgery. Researchers will measure scar formati…

This study looks at whether showering once or twice with a special antiseptic soap before lumbar disc herniation surgery reduces the risk of surgical site infections. 86 participants will be randomly assigned to shower either the night before surgery or both the night before and …

This study looks at two different ways to manage pain after lower back surgery without relying on drugs. About 267 adults will be randomly assigned to either standard care or an enriched pain management plan. The goal is to see which approach better reduces pain and helps people …

This study looks at two ways to numb people for lower back surgery: general anesthesia (being fully asleep) plus a nerve block, or spinal anesthesia (numbing only the lower body) plus a nerve block. The goal is to see which approach helps patients recover better and feel less pai…

This study compares two common procedures for chronic back pain caused by a slipped disc or narrowed spine: a steroid injection and a nerve-targeting radiofrequency treatment. Researchers will track pain levels in 200 adults right after the procedure and three weeks later. The go…

This study looks at whether a specific nerve block (called an erector spinae plane block) can improve pain control after surgery for a slipped disc in the lower back. Researchers will track pain scores, opioid use, how soon patients can walk, and how long they stay in the hospita…

This study tests whether adding virtual reality (VR) to standard physical therapy helps people recover better after lumbar disc surgery. About 46 adults who had surgery on their lower back will either get standard therapy or standard therapy plus a 20-minute VR session. Researche…

This study compares two types of nerve blocks—quadratus lumborum block and retrolaminar block—for pain after lumbar disc surgery. About 84 adults having elective back surgery will receive one of the two blocks before surgery. Researchers will measure pain scores, opioid use, and …