Could stem cells fix your aching back? new trial tests injection after disc surgery

NCT ID NCT06589271

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage trial tests whether injecting stem cells from donated umbilical cords into the spine can help repair degenerated discs in people with lower back and leg pain. Twenty patients who have not improved with other treatments will receive the injection right after a minimally invasive disc surgery. Researchers will track changes on MRI scans and pain scores over a year to see if the treatment is safe and might help the disc heal.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

human umbilical cord mesenchymal stem cells

What this could lead to

If it works, this could point toward a minimally invasive way to repair damaged spinal discs and reduce the need for repeat surgeries.

What could go wrong

This is a very early (phase 1) trial with only 20 participants, so safety and effectiveness are not yet proven. The study is currently suspended, and stem cell injections carry risks like infection or immune reactions.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

intervertebral disk degenerative disorder lumbar disk degenerative disorder lumbar disk herniation, susceptibility to

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Shanghai General Hospital

    Shanghai, 200080, China