Nerve block may cut opioid use after back surgery
NCT ID NCT07695987
First seen Jul 10, 2026 · Last updated Jul 10, 2026
Summary
This study compares two ways to control pain after a single-level lumbar microdiscectomy (a common back surgery). One group receives an ultrasound-guided nerve block (quadro-iliac plane block) with bupivacaine, while the other gets standard local infiltration of pain medicine at the surgical site. Both groups also have a patient-controlled pain pump. The main goal is to see which approach reduces total opioid use in the first 24 hours after surgery, with additional measures of pain scores, side effects, and recovery quality.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- bupivacaine
- What this could lead to
- If effective, this nerve block could become a standard way to manage pain after back surgery, reducing the need for strong opioids and improving recovery.
- What could go wrong
- This is a small, early-stage trial (60 participants) comparing two established techniques, so the difference may be small or not statistically significant. Nerve blocks carry rare risks like infection or bleeding.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Health Science University İstanbul Kanuni Sultan Süleyman Education and Training Hospital
Istanbul, Istanbul, 34303, Turkey (Türkiye)
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