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Nerve blocks put to the test for chest tube pain

NCT ID NCT07823920

Symptom relief Sponsor: Assiut University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 17, 2026 · Last updated Sep 18, 2026 · Updated 1 time

Summary

Doctors insert a chest tube to drain air or fluid from around the lungs, but the procedure often causes severe pain. This trial compares two ultrasound-guided nerve blocks, the serratus anterior plane block and the erector spinae plane block, to see which one better controls pain during and after tube insertion. Researchers will enroll 80 adults in an emergency department and measure pain scores, opioid use, procedure time, and complications. The goal is to find a safer, more effective way to manage pain without relying heavily on opioids or sedation.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
ultrasound-guided nerve blocks using bupivacaine, either a serratus anterior plane block or an erector spinae plane block
What this could lead to
If the blocks work, emergency doctors could control chest tube pain with less reliance on opioids and sedation, which may mean fewer side effects and faster procedures.
What could go wrong
The trial is small and single-center, so results may not apply everywhere. Nerve blocks can fail, cause bleeding, or in rare cases lead to local anesthetic toxicity.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 80 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jun 2027

An estimate. Start dates often move.

Expected to finish

Dec 2029

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 60 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged ≥18 to =\<60 years presenting to the ED requiring tube thoracostomy. * hemodynamically stable (systolic blood pressure ≥90 mmHg). * Able to provide informed consent. Exclusion Criteria: * Tension pneumothorax or hemodynamic instability requiring immediate tube insertion without time for block performance. * Known allergy or hypersensitivity to local anesthetics. * Infection or cellulitis overlying the intended needle insertion site. * Chronic opioid use/dependence, or substance use disorder that would confound pain and opioid-consumption outcomes. * Psychiatric illness, cognitive impairment, intoxication, or severe traumatic brain injury (GCS \< 13) precluding reliable pain-score reporting or informed consent. * Body mass index ≥ 30 kg/m² (sonoanatomic landmarks less reliable). * Patients with spinal injury. * Patinets with fracture rib.

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Conditions

The condition(s) this trial relates to.

agnosia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Chest tube insertion Pain management Thoracostomy pain management

How to take part

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  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

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Contacts and locations

Locations

  • Assiut University hospital

    Asyut, Egypt

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