Common painkillers may alter key protein in back pain patients
NCT ID NCT07662668
First seen Jun 25, 2026 · Last updated Jun 30, 2026 · Updated 3 times
Summary
This study looks at whether taking NSAIDs (like ibuprofen) changes the level of a protein called periostin in the blood of people with degenerative disc disease. Researchers will compare three groups: patients using NSAIDs, patients not using NSAIDs, and healthy people without back pain. The goal is to better understand how inflammation and tissue repair work in this condition.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
non-steroidal anti-inflammatory drug (NSAID)
What this could lead to
If successful, this could show that NSAIDs lower periostin levels, pointing toward a biomarker to guide treatment for disc disease.
What could go wrong
This is an early observational study, not a treatment trial. It only measures blood markers, so it cannot prove that NSAIDs improve symptoms or slow disease.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Email: •••••@•••••
Locations
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Hong Ji Hee
RECRUITINGDaegu, South Korea
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Email: •••••@•••••