New study aims to cut opioid use after spine surgery with simple nerve block

NCT ID NCT05029726

Recruiting now Symptom relief Sponsor: John O'Toole Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a nerve block called an erector spinae plane block can help control pain and reduce the need for opioid painkillers after minimally invasive lumbar spine surgery. About 125 adults having specific types of back surgery will receive either the nerve block or a placebo. The goal is to see if this approach lowers opioid use and improves recovery.

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Conditions

The condition(s) this trial relates to.

ganglion or cyst of synovium/tendon/bursa Intervertebral Disc Displacement intervertebral disk degenerative disorder lumbar disk degenerative disorder lumbar disk disease lumbar disk herniation, susceptibility to lumbar spinal stenosis popliteal cyst radiculopathy spinal stenosis spondylolisthesis spondylosis Synovial Cyst

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DEGENERATIVE DISC DISEASE DEGENERATIVE INTERVERTEBRAL DISCS DEGENERATIVE SPONDYLOLISTHESIS LUMBAR DISC HERNIATION LUMBAR RADICULOPATHY LUMBAR SPINAL STENOSIS LUMBAR SPINE INSTABILITY LUMBAR SPONDYLOLISTHESIS LUMBAR SPONDYLOSIS SYNOVIAL CYST

Contacts and locations

Locations

Rush University Medical Center
RECRUITING

Chicago, Illinois, 60612, United States

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