LUMBAR SPINAL STENOSIS

This study is testing a surgically implanted metal plate (Minuteman G5) to stabilize the lower spine in people with degenerative conditions causing chronic back and leg pain. About 150 adults will receive the plate and bone graft, then be followed for a year to measure pain, disa…

This study compares local anesthesia (with sedation) to general anesthesia for 1-3 level lumbar decompression surgery in people with lumbar spinal stenosis. Researchers want to see if local anesthesia works as well and leads to better pain and disability outcomes. About 100 adult…

This study tests if applying a steroid during back surgery can lower pain and the need for strong painkillers. About 150 adults having a 1-2 level lumbar laminectomy will be randomly assigned to receive the steroid or not. Researchers will track opioid use, hospital stay length, …

This study looks at whether avoiding opioids during lumbar spine surgery can still control pain well while reducing side effects like nausea and constipation. About 75 adults having elective lower back surgery will be placed into one of three groups based on their anesthesia plan…

This study looks at a procedure called MILD, which uses a small tube and X-ray guidance to relieve pressure on nerves in the lower back caused by lumbar spinal stenosis. Researchers will track 8,000 Medicare patients for two years to see how often they need more surgery or have c…

This study is testing a non-invasive postural therapy program for older veterans with lumbar spinal stenosis, a condition that causes back and leg pain when walking or standing. The program includes using a modified rolling walker and changing sleep positions to relieve symptoms.…

This study tests whether a specific nerve block (erector spinae plane block) can reduce the need for opioid painkillers after minimally invasive lumbar spine surgery. About 125 adults undergoing certain types of back surgery will receive either the nerve block or a placebo. The g…

This study compares two surgeries for lumbar spinal stenosis, a condition that narrows the spine and causes pain and trouble walking. One surgery removes bone to relieve pressure, while the other adds screws for extra stability. The goal is to see which approach gives better pain…

This study looks at whether the natural pulsation of the spinal cord lining (dura) is linked to symptoms in people with lumbar spinal stenosis, a condition where the spinal canal narrows. Researchers will measure pain, disability, and walking ability in 100 adults aged 18-85, and…

This study looks at tissue removed during back surgery to find early signs of a heart condition called transthyretin cardiac amyloidosis (ATTR-CA). Researchers will test over 1,600 adults aged 50 and older who had spine surgery. The goal is to catch the disease early, when treatm…

This study compares two surgical treatments for single-level lumbar spinal stenosis: decompression alone versus decompression with fusion. About 86 adults aged 45-75 with severe stenosis will be randomly assigned to one of the two procedures. The goal is to see if fusion is truly…