LUMBAR SPINAL STENOSIS
Clinical trials for LUMBAR SPINAL STENOSIS explained in plain language.
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New gel aims to stop painful scarring after back surgery
Prevention CompletedThis study tested a new gel called Collabarrier® to see if it can prevent scar tissue from forming after back surgery for herniated discs or spinal stenosis. Sixty-nine adults having their first back surgery were randomly given either the new gel or an existing one. Researchers c…
Matched conditions: LUMBAR SPINAL STENOSIS
Phase: NA • Sponsor: DALIM TISSEN Co., Ltd. • Aim: Prevention
Last updated Jun 27, 2026 07:51 UTC
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New keyhole surgery for back pain may offer faster recovery than traditional open surgery
Symptom relief CompletedThis study compared a newer, less invasive endoscopic surgery to standard open surgery for people with lumbar spinal stenosis, a condition that causes back and leg pain. 36 adults who needed surgery were randomly assigned to one of the two procedures. Researchers measured pain, w…
Matched conditions: LUMBAR SPINAL STENOSIS
Phase: NA • Sponsor: Ain Shams University • Aim: Symptom relief
Last updated Jun 27, 2026 12:28 UTC
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Which rehab works best after back surgery? new study aims to find out
Symptom relief CompletedThis study looked at different rehabilitation programs for 90 adults who had back surgery for degenerative lumbar disease. The goal was to see which rehab approach best reduces nerve pain, helps patients regain function, and improves quality of life. Participants were randomly as…
Matched conditions: LUMBAR SPINAL STENOSIS
Phase: NA • Sponsor: National Taiwan University Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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Less invasive back surgery may offer faster relief for spinal stenosis patients
Symptom relief CompletedThis study compared two surgical approaches for people with a single level of lumbar spinal stenosis (a narrowed spine canal causing leg pain and trouble walking). 96 adults aged 40-75 were randomly assigned to receive either minimally invasive decompression and fusion or traditi…
Matched conditions: LUMBAR SPINAL STENOSIS
Phase: NA • Sponsor: N.N. Priorov National Medical Research Center of Traumatology and Orthopedics • Aim: Symptom relief
Last updated Jun 27, 2026 09:09 UTC
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New back pain procedure could rival standard steroid shots
Symptom relief CompletedThis study compared two procedures for relieving pain from lumbar spinal stenosis, a common cause of back and leg pain in older adults. One group received a newer technique called erector spinae plane block, while the other got a standard caudal epidural steroid injection. Resear…
Matched conditions: LUMBAR SPINAL STENOSIS
Phase: NA • Sponsor: Hatice Çetintürk Şahin • Aim: Symptom relief
Last updated Jun 27, 2026 09:09 UTC
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New pill may ease leg pain from narrowed spine
Symptom relief CompletedThis study tested whether Opalmon tablets can improve symptoms and physical function in 107 adults with acquired lumbar spinal stenosis, a condition where the spinal canal narrows and causes leg pain when walking. Participants took the medication for 8 weeks, and researchers meas…
Matched conditions: LUMBAR SPINAL STENOSIS
Sponsor: Dong-A ST Co., Ltd. • Aim: Symptom relief
Last updated Jun 27, 2026 09:09 UTC
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Common steroid may boost pain relief after spine surgery
Symptom relief CompletedThis study tested whether adding the steroid dexamethasone to a standard nerve block could reduce pain and inflammation after lumbar laminectomy (back surgery). Thirty-six adults undergoing surgery received either the nerve block with dexamethasone or without. The dexamethasone g…
Matched conditions: LUMBAR SPINAL STENOSIS
Phase: PHASE3 • Sponsor: Udayana University • Aim: Symptom relief
Last updated Jun 27, 2026 09:07 UTC
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Less invasive back surgery may be just as good as major fusion
Symptom relief CompletedThis study looked at two types of surgery for people over 50 with a slipped vertebra (spondylolisthesis) and a narrowed spine canal (stenosis). One group had a smaller surgery to take pressure off the nerves (decompression alone), while the other had that plus a fusion with metal…
Matched conditions: LUMBAR SPINAL STENOSIS
Sponsor: Kafrelsheikh University • Aim: Symptom relief
Last updated Jun 27, 2026 09:04 UTC
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Could amniotic fluid beat steroids for spinal stenosis pain?
Symptom relief CompletedThis study tested whether an injection of amniotic fluid, a natural anti-inflammatory, works better than a standard steroid injection for chronic back and leg pain caused by spinal stenosis. Sixty-one adults who had not improved with other treatments were randomly assigned to rec…
Matched conditions: LUMBAR SPINAL STENOSIS
Phase: PHASE1, PHASE2 • Sponsor: University of Utah • Aim: Symptom relief
Last updated Jun 27, 2026 07:51 UTC
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Walking patterns may reveal best recovery signs after spine surgery
Knowledge-focused CompletedThis study looked at 20 people with lumbar spinal stenosis (a narrowing in the spine that can cause leg pain when walking) who were waiting for surgery. Researchers measured their walking patterns and asked about pain, function, and quality of life before and after the operation.…
Matched conditions: LUMBAR SPINAL STENOSIS
Sponsor: Université du Québec à Trois-Rivières • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:31 UTC
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Back surgery showdown: which procedure is better for spinal stenosis?
Knowledge-focused CompletedThis pilot study tested whether a larger trial is possible comparing two standard surgeries for lumbar spinal stenosis with a related condition called spondylolisthesis. The two procedures are decompression alone and decompression with fusion. The study enrolled 70 surgical candi…
Matched conditions: LUMBAR SPINAL STENOSIS
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:30 UTC
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New study reveals hidden frailty in back pain patients
Knowledge-focused CompletedThis study explored how frailty affects people with lumbar spinal stenosis, a common age-related back condition. Researchers measured pain, balance, disability, fear of falling, and quality of life in 91 participants aged 45-80. The goal was to better understand frailty in this g…
Matched conditions: LUMBAR SPINAL STENOSIS
Sponsor: Karabuk University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Pain and depression in back stenosis: new study explores the link
Knowledge-focused CompletedThis completed study from Turkey examined 81 adults aged 45–80 with lumbar spinal stenosis—a condition that causes back and leg pain when walking. Researchers measured pain, disability, sleep quality, depression, and a condition called central sensitization (where the nervous sys…
Matched conditions: LUMBAR SPINAL STENOSIS
Sponsor: Karabuk University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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New study tests if hands-on therapy can keep older adults out of the operating room
Knowledge-focused CompletedThis study looked at whether manual therapy, exercise, and acupuncture can reduce pain and improve walking in older adults with lumbar spinal stenosis, a common cause of back and leg pain. Researchers enrolled 60 participants to see if a larger trial is possible. The goal is to f…
Matched conditions: LUMBAR SPINAL STENOSIS
Phase: NA • Sponsor: University of Pittsburgh • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:04 UTC
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25-Year back surgery study: when is less really more?
Knowledge-focused CompletedThis study looked back at 25 years of medical records from 246 patients aged 50+ with lumbar spinal stenosis (a narrowing in the spine that can cause leg pain and trouble walking). Researchers compared patients who had a less invasive surgery (tubular decompression, with or witho…
Matched conditions: LUMBAR SPINAL STENOSIS
Sponsor: University of Valencia • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Back surgery showdown: which procedure works best?
Knowledge-focused CompletedThis study looked at 50 people with lumbar spinal stenosis to see if simple decompression surgery or a more complex fusion surgery leads to better outcomes. Researchers measured pain, disability, quality of life, and movement using questionnaires and wearable sensors. The goal wa…
Matched conditions: LUMBAR SPINAL STENOSIS
Sponsor: Azienda Usl di Bologna • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC
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Spine surgery may improve posture in lumbar stenosis patients
Knowledge-focused CompletedThis study looked at 72 people with lumbar stenosis who had decompression surgery to relieve leg and back pain. Researchers wanted to see if the surgery also improved their posture, specifically a forward-leaning stance. They used special X-ray imaging to measure changes in spine…
Matched conditions: LUMBAR SPINAL STENOSIS
Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:03 UTC
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Back surgery may not end nerve pain, new study shows
Knowledge-focused CompletedThis study looked at 39 people having lower back surgery for a herniated disc or spinal stenosis. Researchers checked for nerve pain before surgery and again 1, 3, 6, and 12 months after using a simple questionnaire. The goal was to see how common nerve pain is after surgery and …
Matched conditions: LUMBAR SPINAL STENOSIS
Sponsor: Centre Hospitalier de Colmar • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:02 UTC
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Can a simple walking test prove back surgery works?
Knowledge-focused CompletedThis study looked at 40 adults with lumbar spinal stenosis (a narrowing in the spine that causes pain and trouble walking) who were scheduled for surgery. Researchers measured how fast they could walk before and after the operation using a 6-minute walk test. The goal was to see …
Matched conditions: LUMBAR SPINAL STENOSIS
Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:02 UTC
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Study asks: do MRI scans really tell the full story of back pain?
Knowledge-focused CompletedThis study looked at 120 people aged 50 and older with low back pain to see how well MRI-based grading of lumbar spinal stenosis matches what patients report on disability and pain questionnaires. Researchers compared three common questionnaires (Oswestry Disability Index, Istanb…
Matched conditions: LUMBAR SPINAL STENOSIS
Sponsor: Sisli Hamidiye Etfal Training and Research Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC