LUMBAR SPINAL STENOSIS
Clinical trials for LUMBAR SPINAL STENOSIS explained in plain language.
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New gel aims to stop painful scarring after spine surgery
Prevention CompletedThis study tested a gel called Collabarrier® to see if it can prevent scar tissue from forming after back surgery for a herniated disc or spinal stenosis. 69 adults having their first back surgery were given either Collabarrier® or a similar gel (Guardix-sol). The main goal was t…
Matched conditions: LUMBAR SPINAL STENOSIS
Phase: NA • Sponsor: DALIM TISSEN Co., Ltd. • Aim: Prevention
Last updated May 06, 2026 16:14 UTC
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New pain block may rival standard steroid shots for back pain
Symptom relief CompletedThis study tested two treatments for people with lumbar spinal stenosis (a narrowing in the spine that causes leg pain and trouble walking) who did not get better with usual care like physical therapy or medication. Thirty adults received either a newer nerve block (erector spina…
Matched conditions: LUMBAR SPINAL STENOSIS
Phase: NA • Sponsor: Hatice Çetintürk Şahin • Aim: Symptom relief
Last updated May 17, 2026 09:38 UTC
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Less invasive back surgery may offer same relief with faster recovery
Symptom relief CompletedThis study looked at 96 adults aged 40-75 with lower back pain from spinal stenosis. It compared a newer, less invasive surgery to traditional open surgery to see which better improves mobility and reduces pain. Results were tracked for 12 months after surgery.
Matched conditions: LUMBAR SPINAL STENOSIS
Phase: NA • Sponsor: N.N. Priorov National Medical Research Center of Traumatology and Orthopedics • Aim: Symptom relief
Last updated May 15, 2026 11:54 UTC
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New hope for spinal stenosis sufferers? opalmon tablet study shows promise
Symptom relief CompletedThis study looked at whether the drug Opalmon (limaprost alfadex) can help people with acquired lumbar spinal stenosis, a condition that causes back and leg pain when walking. 107 adults took the tablet for 8 weeks. Researchers measured changes in symptom severity, physical funct…
Matched conditions: LUMBAR SPINAL STENOSIS
Sponsor: Dong-A ST Co., Ltd. • Aim: Symptom relief
Last updated May 15, 2026 11:54 UTC
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New keyhole back surgery may offer faster recovery for spinal stenosis patients
Symptom relief CompletedThis study compared a newer, less invasive keyhole surgery (endoscopic decompression) with traditional open back surgery for people with lumbar spinal stenosis, a condition that causes leg pain and trouble walking. Thirty-six adults who needed surgery were randomly assigned to on…
Matched conditions: LUMBAR SPINAL STENOSIS
Phase: NA • Sponsor: Ain Shams University • Aim: Symptom relief
Last updated May 13, 2026 16:02 UTC
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Amniotic fluid injection may offer safer pain relief for spinal stenosis
Symptom relief CompletedThis study tested whether an injection of sterile amniotic fluid into the spine can reduce pain and disability in people with spinal stenosis who haven't gotten relief from physical therapy or medications. Sixty-one adults received either the amniotic fluid or a standard steroid …
Matched conditions: LUMBAR SPINAL STENOSIS
Phase: PHASE1, PHASE2 • Sponsor: University of Utah • Aim: Symptom relief
Last updated May 11, 2026 20:48 UTC
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Less surgery may be better for slipped spine bones
Symptom relief CompletedThis study looked at 52 people over 50 with a slipped spine bone and narrowed spinal canal causing leg pain. It compared a smaller surgery that just takes pressure off the nerves to a bigger surgery that also fuses the bones together. The goal was to see which approach better rel…
Matched conditions: LUMBAR SPINAL STENOSIS
Sponsor: Kafrelsheikh University • Aim: Symptom relief
Last updated May 06, 2026 16:01 UTC
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Hands-On therapy may help older adults walk Pain-Free without surgery
Symptom relief CompletedThis study looked at whether a combination of hands-on therapy, exercise, and acupuncture can reduce pain and improve walking in older adults with lumbar spinal stenosis, a common cause of leg pain when walking. Researchers enrolled 60 participants to test if this approach could …
Matched conditions: LUMBAR SPINAL STENOSIS
Phase: NA • Sponsor: University of Pittsburgh • Aim: Symptom relief
Last updated May 04, 2026 16:20 UTC
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Can a simple walking test prove back surgery works?
Knowledge-focused CompletedThis study looked at 40 adults with lumbar spinal stenosis (a narrowing in the lower spine that causes pain and trouble walking) who were scheduled for surgery. Researchers measured how fast they could walk before and after the operation using a 6-minute walk test. The goal was t…
Matched conditions: LUMBAR SPINAL STENOSIS
Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Knowledge-focused
Last updated May 17, 2026 09:50 UTC
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Back Surgery's hidden nerve pain revealed in new study
Knowledge-focused CompletedThis study looked at how common nerve-related pain is after lower back surgery. 39 adults having planned surgery for a herniated disc or spinal stenosis filled out a pain questionnaire before surgery and again up to a year later. The goal was to see if surgery changes the chance …
Matched conditions: LUMBAR SPINAL STENOSIS
Sponsor: Centre Hospitalier de Colmar • Aim: Knowledge-focused
Last updated May 17, 2026 09:39 UTC
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Back surgery showdown: which procedure works best for spinal stenosis?
Knowledge-focused CompletedThis study looked at 50 people with lumbar spinal stenosis (a narrowing of the spine that causes back and leg pain) to see which surgery works better: decompression alone or decompression plus fusion. Researchers measured pain, disability, balance, and walking ability using quest…
Matched conditions: LUMBAR SPINAL STENOSIS
Sponsor: Azienda Usl di Bologna • Aim: Knowledge-focused
Last updated May 17, 2026 09:36 UTC
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Frailty in back pain patients: new insights from completed study
Knowledge-focused CompletedThis study examined frailty and related physical and psychological factors in 91 adults aged 45-80 with lumbar spinal stenosis, a common age-related back condition. Researchers measured pain, balance, disability, fear of falling, and quality of life to better understand how frail…
Matched conditions: LUMBAR SPINAL STENOSIS
Sponsor: Karabuk University • Aim: Knowledge-focused
Last updated May 17, 2026 09:34 UTC
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Back pain study: do MRI scans tell the whole story?
Knowledge-focused CompletedThis study looked at 120 adults aged 50 and older with low back pain to see if the narrowing seen on MRI matches what patients report on questionnaires about their pain and daily function. Researchers compared three common patient surveys with two MRI grading systems. The goal wa…
Matched conditions: LUMBAR SPINAL STENOSIS
Sponsor: Sisli Hamidiye Etfal Training and Research Hospital • Aim: Knowledge-focused
Last updated May 15, 2026 11:57 UTC
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Researchers track walking patterns to predict back surgery recovery
Knowledge-focused CompletedThis study followed 20 people with lumbar spinal stenosis who were waiting for back surgery. Researchers measured how well they walked and how their symptoms changed before and after the operation. The goal was to find which walking tests best show improvement after surgery.
Matched conditions: LUMBAR SPINAL STENOSIS
Sponsor: Université du Québec à Trois-Rivières • Aim: Knowledge-focused
Last updated May 14, 2026 12:06 UTC
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Study reveals hidden link between back pain and depression
Knowledge-focused CompletedThis study looked at 81 adults aged 45-80 with lumbar spinal stenosis, a condition that causes long-term back and leg pain. Researchers measured pain, disability, sleep quality, and depression to see how they relate to central sensitization—a state where the nervous system become…
Matched conditions: LUMBAR SPINAL STENOSIS
Sponsor: Karabuk University • Aim: Knowledge-focused
Last updated May 14, 2026 12:05 UTC
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25-Year study reveals which back surgery patients may need more extensive procedures
Knowledge-focused CompletedThis study looked back at 246 patients aged 50+ with lumbar spinal stenosis who had either a less invasive surgery (tubular decompression) or a more extensive fusion (TLIF) over 25 years. The goal was to see how often the less invasive approach was enough and what factors led to …
Matched conditions: LUMBAR SPINAL STENOSIS
Sponsor: University of Valencia • Aim: Knowledge-focused
Last updated May 14, 2026 12:04 UTC