New pill may ease leg pain from narrowed spine

NCT ID NCT06654856

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether Opalmon tablets can improve symptoms and physical function in 107 adults with acquired lumbar spinal stenosis, a condition where the spinal canal narrows and causes leg pain when walking. Participants took the medication for 8 weeks, and researchers measured changes using a standard questionnaire. The study was observational, meaning there was no comparison group, so results are preliminary.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Opalmon (limaprost alfadex) tablet
What this could lead to
If effective, Opalmon could offer a non-surgical option to ease leg pain and improve walking ability in people with lumbar spinal stenosis.
What could go wrong
This is a small, single-group observational study with no placebo comparison, so results may be less reliable. Benefits may be modest or not apply to all patients.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • VHS Medical Center

    Seoul, South Korea

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