Could amniotic fluid beat steroids for spinal stenosis pain?
NCT ID NCT04537026
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tested whether an injection of amniotic fluid, a natural anti-inflammatory, works better than a standard steroid injection for chronic back and leg pain caused by spinal stenosis. Sixty-one adults who had not improved with other treatments were randomly assigned to receive either the amniotic fluid or a steroid. The goal was to see if the amniotic fluid could reduce pain and disability with fewer side effects.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
amniotic fluid allograft
What this could lead to
If it works, this could offer a safer, longer-lasting option for chronic back and leg pain from spinal stenosis, helping people avoid surgery.
What could go wrong
This is an early-phase trial with only 61 people, so results may not apply widely. The amniotic fluid treatment might not be more effective than the standard steroid injection.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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University of Utah Orthopaedic Center
Salt Lake City, Utah, 84108, United States