Common steroid may boost pain relief after spine surgery

NCT ID NCT07429708

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether adding the steroid dexamethasone to a standard nerve block could reduce pain and inflammation after lumbar laminectomy (back surgery). Thirty-six adults undergoing surgery received either the nerve block with dexamethasone or without. The dexamethasone group had longer pain relief, lower pain scores, and less need for opioid painkillers. The results suggest dexamethasone may be a useful addition to improve recovery after spine surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
dexamethasone
What this could lead to
If it works, this could provide a simple, low-cost way to improve pain control and reduce opioid use after back surgery.
What could go wrong
This is a small, single-center trial with only 36 participants. Results may not apply to all patients, and dexamethasone carries risks like infection or blood sugar changes.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Ngoerah General Hospital

    Denpasar, Bali, 80113, Indonesia

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