Could local anesthesia replace general for back surgery?
NCT ID NCT04992572
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether local anesthesia with sedation works as well as general anesthesia for 1-3 level lumbar decompression surgery. Researchers will measure changes in pain and disability in 100 adults aged 40-95. The goal is to find a safer, effective alternative to general anesthesia.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Propofol and Lidocaine
- What this could lead to
- If successful, this could show that local anesthesia is a safe and effective alternative to general anesthesia for certain back surgeries, potentially reducing recovery time and side effects.
- What could go wrong
- This is a very early-phase trial with only 100 participants, so results may not apply to everyone. Local anesthesia may not provide enough pain control for all patients.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Outpatient Surgery Center/Stanford Spine Clinic
RECRUITINGRedwood City, California, 94063, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Stanford Outpatient surgery center
RECRUITINGRedwood City, California, 94608, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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