Could local anesthesia replace general for back surgery?

NCT ID NCT04992572

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether local anesthesia with sedation works as well as general anesthesia for 1-3 level lumbar decompression surgery. Researchers will measure changes in pain and disability in 100 adults aged 40-95. The goal is to find a safer, effective alternative to general anesthesia.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Propofol and Lidocaine
What this could lead to
If successful, this could show that local anesthesia is a safe and effective alternative to general anesthesia for certain back surgeries, potentially reducing recovery time and side effects.
What could go wrong
This is a very early-phase trial with only 100 participants, so results may not apply to everyone. Local anesthesia may not provide enough pain control for all patients.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Outpatient Surgery Center/Stanford Spine Clinic

    RECRUITING

    Redwood City, California, 94063, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Stanford Outpatient surgery center

    RECRUITING

    Redwood City, California, 94608, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

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