GASTRIC CANCER

This study is testing whether adding an experimental drug called TST001 to standard chemotherapy and immunotherapy works better for advanced stomach or gastroesophageal junction cancer. It will involve 820 adults whose tumors have a specific marker called Claudin18.2. The goal is…

This study is testing a new combination of treatments for early-stage stomach cancer. It adds a shorter course of radiation to standard chemotherapy, all given before surgery. Researchers hope this approach will more completely eliminate the tumor and cause fewer severe side effe…

This study aims to find out if a newer, less invasive robotic surgery is as safe as the current standard laparoscopic (keyhole) surgery for removing part of the stomach in early-stage cancer. About 538 patients will be randomly assigned to receive one of the two surgical methods.…

This study is testing whether adding one or two newer drugs to standard chemotherapy before surgery helps shrink stomach tumors more effectively. It will involve 118 adults with locally advanced stomach cancer who haven't had prior treatment for their advanced disease. Researcher…

This study is testing a new combination of two immunotherapy drugs (Iparomlimab/Tuvonralimab) with a chemotherapy drug for people with advanced stomach or gastroesophageal junction cancer. It's for patients whose cancer has continued to grow or who couldn't tolerate their first s…

This study is testing whether adding a new drug called ivonescimab to standard chemotherapy (SOX) before and after surgery works better than standard chemo alone for people with locally advanced stomach cancer. About 154 participants will be randomly assigned to receive either th…

This study is testing a new fluorescent dye designed to help surgeons see the exact edges of stomach cancer tumors during surgery. The dye is meant to stick to cancer cells and glow under special near-infrared light, potentially making tumor removal more precise. Researchers will…

This study is testing if a new anesthesia drug called remimazolam can reduce confusion (postoperative delirium) in patients 65 and older after stomach cancer surgery. It will compare remimazolam against a standard anesthesia mix in 170 patients. The main goal is to see if the new…

This study aims to find the best way to manage pain after minimally invasive stomach cancer surgery. It will compare two established methods: a numbing injection guided by ultrasound versus a special gel applied directly to the surgical site. The goal is to see which method provi…

This study aims to find out if using MRI scans, instead of or alongside standard CT scans, can help doctors plan and adjust radiotherapy for cancer more precisely. It will involve up to 165 people, including healthy volunteers and patients with cancers like brain, stomach, and pa…

This study aims to understand how well a blood test can detect tiny amounts of leftover cancer DNA after surgery. It will follow 840 patients with breast, lung, prostate, ovarian, or gastric cancer to see if this 'liquid biopsy' can predict if the cancer might come back. The stud…