Stomach cancer trial combines chemo and quick radiation to boost remission
NCT ID NCT07101666
First seen Jun 25, 2026 · Last updated Aug 07, 2026 · Updated 3 times
Summary
This phase 2 trial tests giving short course radiation therapy along with standard chemotherapy before surgery for stomach cancer. The goal is to see if this total neoadjuvant therapy leads to a higher rate of complete cancer disappearance, with fewer side effects than traditional radiation after surgery. About 20 newly diagnosed patients will participate.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- short course radiation therapy and standard chemotherapy (CAPOX, FOLFOX, or FLOT)
- What this could lead to
- If successful, this approach could increase the chance of eliminating all cancer before surgery, potentially improving long-term outcomes for gastric cancer patients.
- What could go wrong
- This is a small, early-phase trial with only 20 participants, so results may not apply broadly. Adding radiation could also increase side effects despite aiming for less toxicity.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Dana Farber Cancer Institute
Boston, Massachusetts, 02215, United States
-
Moffitt Cancer Center
Tampa, Florida, 33612, United States
-
UCLA
Los Angeles, California, 90095, United States
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Washington University School of Medicine
St Louis, Missouri, 63110, United States
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