Stomach cancer trial combines chemo and quick radiation to boost remission

NCT ID NCT07101666

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 2 trial tests giving short course radiation therapy along with standard chemotherapy before surgery for stomach cancer. The goal is to see if this total neoadjuvant therapy leads to a higher rate of complete cancer disappearance, with fewer side effects than traditional radiation after surgery. About 20 newly diagnosed patients will participate.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

short course radiation therapy and standard chemotherapy (CAPOX, FOLFOX, or FLOT)

What this could lead to

If successful, this approach could increase the chance of eliminating all cancer before surgery, potentially improving long-term outcomes for gastric cancer patients.

What could go wrong

This is a small, early-phase trial with only 20 participants, so results may not apply broadly. Adding radiation could also increase side effects despite aiming for less toxicity.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

gastric adenocarcinoma gastric cancer gastric neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

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Locations

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

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  • Moffitt Cancer Center

    Tampa, Florida, 33612, United States

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  • UCLA

    Los Angeles, California, 90095, United States

    Contact Phone: •••-•••-••••

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  • Washington University School of Medicine

    St Louis, Missouri, 63110, United States

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    Contact Phone: •••-•••-•••• Email: •••••@•••••

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