Could a simple painkiller combo replace opioids after stomach cancer surgery?

NCT ID NCT07687394

Not yet recruiting Symptom relief Sponsor: Yonsei University Source: ClinicalTrials.gov ↗

First seen Jul 07, 2026 · Last updated Jul 08, 2026 · Updated 1 time

Summary

This trial compares a fixed-dose combination of acetaminophen and ibuprofen (Maxigesic) against acetaminophen alone for pain relief after minimally invasive stomach cancer surgery. 160 adults scheduled for radical gastrectomy will receive either the combo or standard acetaminophen every 6 hours for 48 hours after surgery. The goal is to see if the combination reduces pain scores and opioid use, potentially offering a safer, non-opioid alternative.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: acetaminophen/ibuprofen (Maxigesic IV)
What this could lead to: If it works, this could offer a more effective, opioid-sparing pain management option for people recovering from stomach cancer surgery.
What could go wrong: This is a phase 4 trial with 160 participants, so results may not apply to all patients. The combination may not prove superior and could carry risks like bleeding or kidney issues.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

gastric cancer gastric neoplasm Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PAIN POSTOPERATIVE STOMACH NEOPLASMS

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

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