New drug cocktail aims to fight stomach cancer when first treatment fails

NCT ID NCT07139587

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This clinical trial tests a combination of two immunotherapy drugs (Iparomlimab and Tuvonralimab) plus chemotherapy (albumin-bound paclitaxel) as a second-line treatment for advanced stomach or gastroesophageal junction cancer. The study will enroll 30 adults whose cancer has worsened or who could not tolerate first-line treatment. The goal is to see if this combination can shrink tumors and extend survival.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Iparomlimab/Tuvonralimab (immunotherapy) combined with albumin-bound paclitaxel (chemotherapy)

What this could lead to

If successful, this could offer a new second-line treatment option for advanced stomach cancer, potentially extending life and controlling the disease.

What could go wrong

This is a very small, early-phase trial with only 30 participants. The combination may not work better than existing options and could cause significant side effects from both immunotherapy and chemotherapy.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

gastric adenocarcinoma gastric cancer gastric neoplasm gastroesophageal junction adenocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Hebei General Hospital

    Shijiazhuang, Hebei, 050000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact