CRITICAL ILLNESS
Clinical trials for CRITICAL ILLNESS explained in plain language.
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New program aims to help patients and families recover after ICU trauma
Disease control TerminatedThis study is testing a new support program for people recovering after a serious illness that required intensive care (ICU). The program provides telehealth check-ins to help with health management, rehabilitation, social support, and care coordination for patients and their fam…
Matched conditions: CRITICAL ILLNESS
Phase: NA • Sponsor: University of Pittsburgh • Aim: Disease control
Last updated Mar 31, 2026 12:12 UTC
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Can getting kids moving in the ICU help them heal faster?
Disease control OngoingThis study is testing a program called 'PICU Up!' that aims to help critically ill children in the intensive care unit recover better. The program bundles together promoting sleep, preventing confusion, and safely reducing sedation to allow kids to start moving and sitting up ear…
Matched conditions: CRITICAL ILLNESS
Phase: NA • Sponsor: Johns Hopkins University • Aim: Disease control
Last updated Mar 27, 2026 12:40 UTC
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Robot doctor takes over oxygen control in hospitals
Disease control OngoingThis study is testing whether an automated system can better control oxygen levels for hospitalized patients with serious injuries or illnesses. It compares the AI system, which adjusts oxygen flow automatically, to the standard method where nurses manually adjust it. The goal is…
Matched conditions: CRITICAL ILLNESS
Phase: NA • Sponsor: University of Colorado, Denver • Aim: Disease control
Last updated Mar 25, 2026 14:08 UTC
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New fluid control strategy tested in ICU to help failing kidneys
Disease control OngoingThis study is testing a new, more active plan to manage fluid levels in critically ill patients whose kidneys have stopped working and require dialysis. It compares this planned approach to the usual care doctors provide. The goal is to see if carefully controlling fluid buildup …
Matched conditions: CRITICAL ILLNESS
Phase: NA • Sponsor: Centre hospitalier de l'Université de Montréal (CHUM) • Aim: Disease control
Last updated Mar 24, 2026 12:02 UTC
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VR headsets in the ICU: a new tool to heal the mind after critical illness
Symptom relief OngoingThis study is testing a special virtual reality (VR) program designed to help patients in the intensive care unit (ICU). The program aims to provide mental exercises and emotional support to make the ICU stay more comfortable and to improve patients' memory, thinking skills, and …
Matched conditions: CRITICAL ILLNESS
Phase: NA • Sponsor: University of the Balearic Islands • Aim: Symptom relief
Last updated Mar 30, 2026 14:35 UTC
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New nursing care package aims to soothe ICU stress and speed recovery
Symptom relief OngoingThis study is testing a new 'Comfort Care Package' designed to reduce stress and improve comfort for patients in intensive care units (ICUs). The package is being compared to standard ICU care in 88 patients in Turkey. Researchers hope that by making patients more comfortable, it…
Matched conditions: CRITICAL ILLNESS
Phase: NA • Sponsor: Akdeniz University • Aim: Symptom relief
Last updated Mar 27, 2026 12:38 UTC
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Brain clockwork: can timing computer games boost recovery after ICU?
Symptom relief OngoingThis study is testing whether doing computerized brain training exercises in the morning or late afternoon works better for older adults recovering from a stay in the intensive care unit (ICU). Researchers want to see if the timing of these exercises can help improve thinking ski…
Matched conditions: CRITICAL ILLNESS
Phase: NA • Sponsor: University of Washington • Aim: Symptom relief
Last updated Mar 23, 2026 15:17 UTC
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Can adding muscle stimulation boost ICU recovery?
Symptom relief OngoingThis study is testing whether adding electrical muscle stimulation to standard bike exercises helps intensive care patients recover faster. Researchers are comparing two groups of 24 stable ICU patients: one doing bike exercises alone, and another doing bike exercises plus muscle…
Matched conditions: CRITICAL ILLNESS
Phase: NA • Sponsor: Hacettepe University • Aim: Symptom relief
Last updated Mar 23, 2026 15:17 UTC
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Researchers track muscle wasting in ventilated ICU patients
Knowledge-focused ENROLLING_BY_INVITATIONThis study aims to understand how common severe muscle loss (sarcopenia) is in ICU patients who need breathing machines for more than two days. Researchers will measure muscle mass and strength when patients enter the ICU and track if they develop additional weakness during their…
Matched conditions: CRITICAL ILLNESS
Sponsor: Hospital Mutua de Terrassa • Aim: Knowledge-focused
Last updated Apr 02, 2026 01:41 UTC
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Simple scan could predict recovery for frail ICU patients
Knowledge-focused ENROLLING_BY_INVITATIONThis study aims to understand if measuring thigh muscle thickness with a simple, bedside ultrasound scan can help predict frailty, malnutrition risk, and length of hospital stay in elderly patients who are critically ill. Researchers will observe 80 patients aged 65 and over in a…
Matched conditions: CRITICAL ILLNESS
Sponsor: Ankara Training and Research Hospital • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:41 UTC
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Doctors surveyed on heartbreaking choices for critically ill children
Knowledge-focused OngoingThis study aims to understand the attitudes of Swedish pediatric intensive care doctors when making the difficult decision to stop or not start life-sustaining treatments for critically ill children. Researchers are surveying 100 doctors working in Swedish intensive care units. T…
Matched conditions: CRITICAL ILLNESS
Sponsor: Göteborg University • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:41 UTC
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Study probes link between 'Do not Resuscitate' orders and ICU deaths
Knowledge-focused OngoingThis study looks back at the medical records of 1,500 critically ill patients to understand if having a 'do not resuscitate' order is connected to a higher chance of dying. Researchers will check if this link holds true even after considering factors like the patient's age, sex, …
Matched conditions: CRITICAL ILLNESS
Sponsor: Karolinska Institutet • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:11 UTC
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Scientists gauge hidden effort of ICU bed exercises
Knowledge-focused OngoingThis study aims to measure how much energy bedridden patients on breathing machines use during standard physical therapy in the ICU. Researchers will monitor 40 critically ill adults using a special device on their ventilator that tracks oxygen use. The goal is to understand the …
Matched conditions: CRITICAL ILLNESS
Sponsor: Universidad de Extremadura • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:33 UTC
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Tracking the hidden scars of severe COVID-19
Knowledge-focused OngoingThis study aims to understand the long-term physical and mental health challenges faced by people who survive severe COVID-19 with respiratory failure. Researchers will follow 500 patients for up to a year after leaving the hospital, comparing them to other ICU patients without C…
Matched conditions: CRITICAL ILLNESS
Sponsor: University of Chicago • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:33 UTC
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Brain fog after trauma: study tracks why young survivors struggle to return to work
Knowledge-focused OngoingThis study aims to understand why many people develop long-term thinking and memory problems after surviving a serious injury and ICU stay. Researchers are following 432 trauma patients to see how factors like confusion in the hospital (delirium) and body-wide inflammation affect…
Matched conditions: CRITICAL ILLNESS
Sponsor: Vanderbilt University Medical Center • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:33 UTC
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Sweden tracks 7,500 COVID ICU survivors for Long-Term health risks
Knowledge-focused OngoingThis study aims to understand the long-term health of people who were critically ill with COVID-19 and needed intensive care in Sweden. Researchers are tracking the survival and new heart or lung problems in over 7,500 patients for up to a year after their ICU stay. They are also…
Matched conditions: CRITICAL ILLNESS
Sponsor: Linkoeping University • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:30 UTC
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Hidden damage? study probes Long-Term health of ICU survivors
Knowledge-focused TerminatedThis study aims to better understand the long-term health of people who survive a long stay in the intensive care unit (ICU). Researchers will closely monitor 100 former ICU patients to see how their kidney function, muscle mass, and bone health change over time. The goal is to g…
Matched conditions: CRITICAL ILLNESS
Sponsor: University of Liege • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:28 UTC
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Scientists track gut health in ICU to predict patient recovery
Knowledge-focused OngoingThis study aims to understand how the community of bacteria in the gut changes when a person is critically ill in the hospital. Researchers will collect stool samples from 500 adult patients in the intensive care unit and track their health for a year after discharge. The goal is…
Matched conditions: CRITICAL ILLNESS
Sponsor: University of Chicago • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:27 UTC
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Doctors test new italian tool to track ICU recovery
Knowledge-focused OngoingThis study is creating and testing an Italian version of a tool that measures how well intensive care patients can move. Researchers will use the tool with 100 ICU patients to see if it accurately tracks mobility recovery. The goal is to help healthcare workers better assess pati…
Matched conditions: CRITICAL ILLNESS
Sponsor: Istituto Clinico Humanitas • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:38 UTC
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Digital lifeline: new system aims to stop medical errors when patients move between hospitals
Knowledge-focused ENROLLING_BY_INVITATIONThis study is testing a new digital platform designed to improve how patient information is shared when someone is transferred between different hospitals. The goal is to make sure doctors at the receiving hospital have all the necessary details to provide safe, continuous care. …
Matched conditions: CRITICAL ILLNESS
Phase: NA • Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:38 UTC
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Can a simple nutrition check predict recovery in frail ICU patients?
Knowledge-focused ENROLLING_BY_INVITATIONThis study aims to understand the link between nutritional status and frailty in older patients who are critically ill and in the intensive care unit (ICU). Researchers will observe 100 patients over 65 to see if standard nutrition scores can help predict their health outcomes. T…
Matched conditions: CRITICAL ILLNESS
Sponsor: Ankara Training and Research Hospital • Aim: Knowledge-focused
Last updated Mar 25, 2026 14:07 UTC
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ICU survivors face hidden dementia risk: groundbreaking study seeks answers
Knowledge-focused OngoingThis study aims to understand why some people who survive serious illness in intensive care units (ICUs) later develop problems with memory and thinking similar to dementia. Researchers will follow 567 new ICU patients and some previous study participants for up to 12 years, usin…
Matched conditions: CRITICAL ILLNESS
Sponsor: Vanderbilt University Medical Center • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:15 UTC
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Can moving in the hospital help seniors bounce back?
Knowledge-focused OngoingThis study aims to understand if being physically active while in the hospital helps older adults recover better after a life-threatening illness. Researchers are tracking 312 patients with conditions like sepsis to see how their activity levels relate to their physical and menta…
Matched conditions: CRITICAL ILLNESS
Sponsor: Vanderbilt University Medical Center • Aim: Knowledge-focused
Last updated Mar 20, 2026 14:47 UTC
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Can amino acid boost turn ICU Patients' bodies from breakdown to rebuild?
Knowledge-focused OngoingThis study is testing whether giving extra amino acids (the building blocks of protein) through an IV can help critically ill patients in the ICU shift their bodies from breaking down muscle to building it up. Researchers will measure protein balance and look for molecular signal…
Matched conditions: CRITICAL ILLNESS
Phase: NA • Sponsor: Arnold Kristof • Aim: Knowledge-focused
Last updated Mar 16, 2026 15:26 UTC