Trauma ICU survivors: new study tracks hidden brain decline

NCT ID NCT03098459

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study follows 432 adults who were in the ICU after a traumatic injury or burn. Researchers want to see if and why patients develop long-term problems with memory, thinking, and daily function. By tracking cognitive skills and inflammation over time, they hope to uncover links between trauma and conditions like dementia.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this study could reveal why some trauma patients develop long-term cognitive issues, pointing toward ways to prevent or treat them.
What could go wrong
This is an observational study, not a treatment trial. It cannot prove cause and effect, and results may take years to translate into real-world help.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Alzheimer disease brain disorder Brain Injuries, Traumatic burn Cognitive Dysfunction Craniocerebral Trauma Critical Illness delirium dementia early-onset autosomal dominant Alzheimer disease Hematoma, Subdural Inflammation injury intracerebral hemorrhage Multiple Trauma Neuroinflammatory Diseases subarachnoid hemorrhage traumatic brain injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Vanderbilt University Medical Center

    Nashville, Tennessee, 37212, United States

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