ICU Survivors' dementia risk under the microscope
NCT ID NCT04305600
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study follows 567 ICU survivors to see how their brain function changes over up to 12 years. Researchers will use brain scans, spinal fluid tests, and brain donations to find out why some people develop dementia after critical illness. The goal is to learn the causes of post-ICU brain decline, not to test a new treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this could reveal why some ICU survivors develop dementia and point to ways to prevent or treat it.
- What could go wrong
- This is an observational study, not a treatment trial. It may not find clear causes or lead directly to new therapies.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for CRITICAL ILLNESS are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Rush University Medical Center
Chicago, Illinois, 60612, United States
-
Vanderbilt University Medical Center
Nashville, Tennessee, 37203, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- AI may predict transfusion needs to shield ICU patients from organ failure
- A simple blood test trend may flag ICU patients at risk
- Could a simple CT scan reveal which ICU cancer patients are at highest risk?
- A gentle touch from family may calm the ICU storm
- Can remote exercise rebuild strength in kids after ICU?
- Fasting in the ICU: a metabolic key to immune response?