ICU Survivors' dementia risk under the microscope
NCT ID NCT04305600
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study follows 567 ICU survivors to see how their brain function changes over up to 12 years. Researchers will use brain scans, spinal fluid tests, and brain donations to find out why some people develop dementia after critical illness. The goal is to learn the causes of post-ICU brain decline, not to test a new treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could reveal why some ICU survivors develop dementia and point to ways to prevent or treat it.
What could go wrong
This is an observational study, not a treatment trial. It may not find clear causes or lead directly to new therapies.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Rush University Medical Center
Chicago, Illinois, 60612, United States
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Vanderbilt University Medical Center
Nashville, Tennessee, 37203, United States