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Waking ICU patients daily may lower blood pressure drug needs

NCT ID NCT03182335

Ongoing Knowledge-focused Sponsor: University of Chicago Source: ClinicalTrials.gov ↗

First seen Jul 13, 2026 · Last updated Jul 14, 2026 · Updated 1 time

Summary

This study looks at whether pausing sedation each day in mechanically ventilated ICU patients can reduce the amount of blood pressure medication they need. Researchers will compare medication doses before and during these daily awakening trials. The goal is to see if this simple practice can help manage blood pressure more effectively and possibly lower the risk of delirium.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
sedation awakening trial (SAT)
What this could lead to
If successful, this could help ICU doctors better manage sedation and blood pressure medications, potentially reducing delirium and improving patient outcomes.
What could go wrong
This is an observational study, not a treatment trial. Results may not change practice and could vary widely among patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Critical Illness delirium hypotensive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CRITICAL ILLNESS DELIRIUM LOW BLOOD PRESSURE

Contacts and locations

Locations

  • The University of Chicago Medical Center

    Chicago, Illinois, 60637, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.